Vasudevan Biju, Verma Rajesh, Badwal Sonia, Pragasam Vijendran, Moorchung Nikhil, Badad Ambresh
Department of Dermatology, Command Hospital (Southern Command), Pune, Maharastra, India.
Indian J Dermatol. 2014 May;59(3):290-2. doi: 10.4103/0019-5154.131408.
Reticulate hyperpigmentary disorders are a group of rare genetic pigmentary abnormalities which includes reticulate acropigmentation of Kitamura (RAPK), Dowling-Degos disease (DD), reticulate acropigmentation of Dohi (RAPD), Haber's syndrome, and Galli-Galli disease. A 25-year-old male presented with asymptomatic dark-colored lesions on his hands and feet with light-colored skin lesions involving the trunk since three years. Dermatological examination revealed hyperpigmented macules in a reticulate pattern involving the dorsa of the hands and feet, front and sides of the neck, axillae, periorbital region, and groin. Multiple pits were present over both palms, with breaks in dermatoglyphics. He also had multiple nonacne facial scars predominantly on the nose and malar areas. The patient had overlapping features of RAPK and DDD. In addition, he also had hypopigmented macules and acneiform facial scars. Such an overlap of features of reticulate pigmentation has not been previously reported in the literature.
网状色素沉着性疾病是一组罕见的遗传性色素异常疾病，包括北村网状肢端色素沉着症（RAPK）、Dowling-Degos病（DD）、土肥网状肢端色素沉着症（RAPD）、哈伯综合征和加利-加利病。一名25岁男性自三年前起双手和双脚出现无症状深色皮损，躯干出现浅色皮肤损害。皮肤科检查发现网状色素沉着斑，累及手背、足背、颈部前方和两侧、腋窝、眶周区域和腹股沟。双侧手掌有多个凹坑，皮纹中断。他还在鼻子和颊部区域有多处非痤疮性面部瘢痕。该患者具有RAPK和DDD的重叠特征。此外，他还有色素减退斑和痤疮样面部瘢痕。这种网状色素沉着特征的重叠此前在文献中未见报道。
