网状色素沉着性疾病的临床重叠：三例病例研究

Clinical Overlaps in Reticulate Pigmentary Disorders: A Study of Three Cases.

作者信息

Malik Nishtha, Nair Rahul S, Reddy Aravind, Chaurasia Pooja, Pillai Niranjana S

机构信息

Dermatology, Venereology, and Leprosy, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune (Deemed to be University), Pune, IND.

Orthopedic Surgery, Holy Cross Hospital, Kollam, IND.

出版信息

Cureus. 2024 Mar 20;16(3):e56600. doi: 10.7759/cureus.56600. eCollection 2024 Mar.

DOI:10.7759/cureus.56600

PMID:38646262

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11031628/

Abstract

Reticulate pigmentary disorders are autosomal dominant pigmentary disorders caused by abnormalities in the keratin 5 and keratin 14 genes. Here, we report three cases of reticulate hyperpigmentation disorders with clinical overlaps of the reticulate acropigmentation of Kitamura, Dowling-Degos disease (DDD), and dyschromatosis symmetrica hereditaria (DSH), all three having limited treatment options.

摘要

网状色素沉着障碍是由角蛋白5和角蛋白14基因异常引起的常染色体显性色素沉着障碍。在此，我们报告3例网状色素沉着过度性疾病，其临床表现与北村网状肢端色素沉着症、Dowling-Degos病（DDD）和遗传性对称性色素异常症（DSH）有重叠，这三种疾病的治疗选择均有限。