Casale V, Casale G, Ferro S, Stigliano V, Bigotti G, Crespi M
Mater Med Pol. 1989 Oct-Dec;21(4):269-73.
In the present report we have analyzed data reported in literature on the diagnostic accuracy of endoscopy and associated sampling techniques compared to standard and double contrast radiological examinations, as well as the rate of malignant transformation of benign gastric ulcer. Data on 117 patients with benign gastric ulcer examined in our Center between 1974 and 1984 are reported. From our experience, we may state that only one case underwent to malignant transformation, i.e. a rate of 1.2%, in agreement with recent literature. Three cases of malignant-ulcer had gone undiagnosed at first endoscopy, but were correctly diagnosed at a short-term re-examination. The present study, other than reconfirming the importance of the endoscopic examination with associated techniques, stresses the importance of aimed cytology and of short-term endoscopic re-examination as a mean for lowering the rate of false negative diagnoses.
在本报告中，我们分析了文献中报道的关于内镜检查及相关采样技术与标准和双重对比放射学检查相比的诊断准确性数据，以及良性胃溃疡的恶变率。报告了1974年至1984年期间在我们中心接受检查的117例良性胃溃疡患者的数据。根据我们的经验，可以说只有1例发生了恶变，即恶变率为1.2%，这与最近的文献一致。3例恶性溃疡在首次内镜检查时未被诊断出来，但在短期复查时被正确诊断。本研究除了再次证实内镜检查及相关技术的重要性外，还强调了有针对性的细胞学检查和短期内镜复查作为降低假阴性诊断率手段的重要性。
