Trägårdh B, Haglund U
Acta Chir Scand. 1985;151(1):37-41.
Examinations at an endoscopy unit in 1976 gave diagnoses of gastric cancer in 31 patients, malignant lymphoma in 3 and new benign gastric ulcer in 223 patients. Correctness of diagnosis was judged to be verified following surgery, autopsy, clinical follow-up or five-year survival. All the malignant lesions were macroscopically and/or microscopically recognized at the first examination, except for one that was then considered to be a submucosal or extragastric tumour, but was correctly diagnosed at surgery prompted by the endoscopic findings. Of the 223 benign ulcers, 219 received a correct diagnosis at the first examination. In the other four cases malignancy was macroscopically or microscopically suspected, but was excluded following surgical excision or repeat examination. Based on these data, the authors suggest that routine endoscopic follow-up of gastric ulcer to exclude malignancy is unnecessary if the primary examination has been performed by an experienced endoscopist, and if both the macroscopic and the microscopic (biopsy) judgement unreservedly are that the lesion is benign.
1976年，一家内镜检查科室对患者进行检查，诊断出31例胃癌、3例恶性淋巴瘤以及223例新发现的良性胃溃疡。诊断的正确性通过手术、尸检、临床随访或五年生存率来判定。除1例最初被认为是黏膜下或胃外肿瘤，但在内镜检查结果提示下手术时被正确诊断的病例外，所有恶性病变在首次检查时均通过肉眼和/或显微镜检查得以识别。在223例良性溃疡患者中，219例在首次检查时得到了正确诊断。另外4例在肉眼或显微镜检查时怀疑有恶性病变，但在手术切除或复查后排除了恶性可能。基于这些数据，作者认为，如果初次检查由经验丰富的内镜医师进行，并且肉眼和显微镜（活检）判断均明确病变为良性，那么对胃溃疡进行常规内镜随访以排除恶性病变是没有必要的。
