Pokorski M, Paulev P E, Głogowska M
Mater Med Pol. 1989 Oct-Dec;21(4):301-4.
There is ample evidence that the ventrolateral medulla (VLM) is involved in regulation of respiration. The VLM is considered to be the site of location of the central respiratory chemoreceptors. Neither neuroanatomical nor neurophysiological coordinates of the chemoreceptor have ever been indisputably identified or verified, despite decades of research. This commentary addresses new hypotheses concerning the process of central chemoreception and recent findings calling into question the exclusivity of VLM for the chemoreceptor location and function. These findings rekindle the possibility of medullary respiratory neurons being chemosensors. Crucial issues concerning the central chemoreception remain unsettled and are open to further research.
有充分证据表明，延髓腹外侧区（VLM）参与呼吸调节。VLM被认为是中枢呼吸化学感受器的定位部位。尽管经过数十年研究，但化学感受器的神经解剖学和神经生理学坐标从未得到过明确识别或验证。本评论探讨了有关中枢化学感受过程的新假说，以及最近对VLM作为化学感受器定位和功能的唯一性提出质疑的研究发现。这些发现重新引发了延髓呼吸神经元作为化学传感器的可能性。有关中枢化学感受的关键问题仍未解决，有待进一步研究。
