Pereira Telmo, Maldonado João, Coutinho Rita, Cardoso Eva, Laranjeiro Mafalda, Andrade Ivo, Conde Jorge
aPolytechnic Institute of Coimbra, ESTES, Department of Cardiopneumology bInstitute of Cardiovascular Research, Coimbra, Portugal.
Blood Press Monit. 2014 Oct;19(5):280-7. doi: 10.1097/MBP.0000000000000058.
Arteries are the target, the place, and the common denominator of cardiovascular diseases; hence, study of arterial function is of greatest importance in clinical practice. The aim of this study was to evaluate the accuracy of carotid pulse wave analysis using the new version of the Complior device--the Complior Analyse.
This was a cross-sectional study that included 15 patients (seven women), mean age 62.07±10.59 years, referenced for cardiac catheterization. Pressure curves were obtained simultaneously in the ascending aorta (invasively) and in the right common carotid artery (using the Complior Analyse). Mean central arterial pressures, augmentation indexes, and wave morphology obtained using both methods were compared. A good concordance between methods was obtained for all the parameters measured, with intraclass correlation coefficients above 0.9. Bland-Altman analysis also indicated a good accuracy profile of the Complior device, with small mean differences observed for all parameters and most values confined within 2 SD of the mean difference. This was further confirmed by the strong Pearson correlation coefficients, with r² coefficients above 0.92 for all the variables studied. The correlations observed were independent of sex, age, arterial pressure, and BMI.
The results presented and available research clearly indicate that the Complior Analyse device measures carotid pressure waves accurately; therefore, it is a simple and reliable noninvasive alternative for pressure wave analysis.
动脉是心血管疾病的靶点、发病部位及共同特征；因此，动脉功能研究在临床实践中至关重要。本研究旨在评估使用新版Complior设备（Complior Analyse）进行颈动脉脉搏波分析的准确性。
这是一项横断面研究，纳入了15例患者（7名女性），平均年龄62.07±10.59岁，均因心脏导管插入术而接受检查。同时在升主动脉（通过侵入性方法）和右颈总动脉（使用Complior Analyse）获取压力曲线。比较了两种方法测得的平均中心动脉压、增强指数和波形形态。对于所有测量参数，两种方法之间均具有良好的一致性，组内相关系数均高于0.9。Bland-Altman分析也表明Complior设备具有良好的准确性，所有参数的平均差异较小，且大多数值均在平均差异的2个标准差范围内。所有研究变量的Pearson相关系数均较高（r²系数均高于0.92），进一步证实了这一点。观察到的相关性不受性别、年龄、动脉压和体重指数的影响。
所呈现的结果及现有研究清楚地表明，Complior Analyse设备能够准确测量颈动脉压力波；因此，它是一种简单且可靠的压力波分析无创替代方法。
