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碳化硅的致病和致癌特性。

Pathogenic and carcinogenic properties of silicon carbide.

作者信息

Cichy B

出版信息

Pol J Occup Med. 1989;2(1):87-96.

PMID:2489417
Abstract

The article presents the influence of silicon carbide upon an organism, on the basis of the publications which, according to Chemical Abstracts, appeared on this subject from 1944 until 1987. The insolubility of silicon carbide, in the liquids of an organism and its indigestibility are indicated. A connection is presented between the size and shape of micrograins and the probability of tumor formation in rats; and the difference between silicon carbide and other dusts in the absorption of x-rays, inhibition of the TTC-dehydrogenase activity, collagenisation of lesions, carcinogenicity are also presented. The problem of interpretation of radiological images of lungs in people exposed to the influence of carborundum dust is dealt with. The biological inertness of silicon carbide is questioned.

摘要

本文基于化学文摘中1944年至1987年期间发表的关于该主题的文献,介绍了碳化硅对生物体的影响。文中指出了碳化硅在生物体内液体中的不溶性及其不可消化性。还阐述了微粒的大小和形状与大鼠肿瘤形成概率之间的联系;同时也介绍了碳化硅与其他粉尘在X射线吸收、TTC脱氢酶活性抑制、损伤胶原化、致癌性方面的差异。探讨了接触金刚砂粉尘人群肺部放射影像的解读问题。对碳化硅的生物惰性提出了质疑。

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Pathogenic and carcinogenic properties of silicon carbide.碳化硅的致病和致癌特性。
Pol J Occup Med. 1989;2(1):87-96.
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