Li Peixin, Zhang Zhongtao, Li Jianshe, Jin Lan, Han Wei, Zhang Jie
Department of Comprehensive Surgery, Medical and Health Center, Beijing Friendship Hospital affiliated to Capital Medical University, Beijing, China (mainland).
Department of General Surgery, Beijing Friendship Hospital Affiliated to Capital Medical Universit, Beijing, China (mainland).
Med Sci Monit. 2014 Jun 4;20:920-6. doi: 10.12659/MSM.890831.
The aim of this study was to evaluate the diagnostic potential of magnetic resonance cholangiopancreatography (MRCP) in preoperative patients with secondary common bile duct stones during the application of laparoscopic trans-cystic common bile duct exploration (LTCBDE).
The clinical records of 255 patients were retrospectively analyzed. All patients included in the study were examined by MRCP 3 days prior to LTCBDE.
Secondary bile duct stones were detected in 220 patients using LTCBDE. Of the patients diagnosed by MRCP, 141 were true-positive, 28 were true-negative, 7 were false-positive and 79 were false-negative. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of MRCP for secondary common bile duct stones were 64.09%, 80.00%, 66.27%, 95.27%, and 26.17%, respectively. When the cases with muddy stones were excluded, the outcomes were 80.41%, 79.41%, 69.23%, 94.44%, and 48.21%, respectively. When cases with stones <3 mm (inclusive) in diameter were excluded, the outcomes were 93.75%, 79.41%, 86.27%, 93.75%, and 65.85%, respectively. When cases with stones <5 mm (inclusive) in diameter were excluded, the outcomes were 93.10%, 79.41%, 89.26%, 92.05%, and 81.82%, respectively.
The effectiveness of preoperative MRCP is overestimated for the diagnosis of secondary common bile duct stones, particularly for muddy and micro-stones.
本研究旨在评估磁共振胰胆管造影(MRCP)在腹腔镜经胆囊管胆总管探查术(LTCBDE)应用中对术前继发性胆总管结石患者的诊断潜力。
回顾性分析255例患者的临床记录。纳入研究的所有患者在LTCBDE术前3天接受MRCP检查。
220例患者通过LTCBDE检测出继发性胆管结石。在经MRCP诊断的患者中,141例为真阳性,28例为真阴性,7例为假阳性,79例为假阴性。MRCP对继发性胆总管结石的敏感性、特异性、准确性、阳性预测值和阴性预测值分别为64.09%、80.00%、66.27%、95.27%和26.17%。排除泥沙样结石病例后,各项结果分别为80.41%、79.41%、69.23%、94.44%和48.21%。排除直径<3 mm(含)的结石病例后,各项结果分别为93.75%、79.41%、86.27%、93.75 %和65.85%。排除直径<5 mm(含)的结石病例后,各项结果分别为93.10%、79.41%、89.26%、92.05%和81.82%。
术前MRCP对继发性胆总管结石诊断的有效性被高估,尤其是对泥沙样结石和微小结石。