Cimadevilla J M, González-Pardo H, López L, Diaz F, Cueto E G, Garcia-Moreno L M, Arias J L
Laboratorio de Psicobiologı́a, Facultad de Psicologı́a, Universidad de Oviedo, E-33003 Oviedo, Spain.
Departamento de Biologı́a Funcional (Area de Fisiologı́a), Universidad de Oviedo, Oviedo, Spain.
Behav Processes. 1999 Jun;46(2):159-71. doi: 10.1016/s0376-6357(99)00034-0.
Some authors have reported that male rats younger than 21 days old are unable to perform spatial learning correctly because they have still not developed the ability to use extra-maze cues. In experiment 1, we analyzed spatial learning in 14-, 21-, 30- and 42-day-old rats using the Morris water maze (MWM). According to our results, a good performance was observed in 30-day-old male rats whereas this was not observed in female rats until they were 42 days old. In experiment 2 we studied the role of sex hormones in this kind of learning using the MWM and 30-day-old rats (castrated male rats and female rats treated with testosterone propionate (TP) after birth). The latter group, the male control group and the castrated males all solved the task correctly. The objective of experiment 3 was to determine possible differences between the sexes in the use of taxon strategies in the T water maze. To summarize, sexual dimorphism was only observed in spatial learning during development.
一些作者报告称，21日龄以下的雄性大鼠无法正确进行空间学习，因为它们尚未发展出利用迷宫外部线索的能力。在实验1中，我们使用莫里斯水迷宫（MWM）分析了14日龄、21日龄、30日龄和42日龄大鼠的空间学习能力。根据我们的结果，30日龄的雄性大鼠表现良好，而雌性大鼠直到42日龄才表现出良好的空间学习能力。在实验2中，我们使用MWM和30日龄大鼠（阉割的雄性大鼠和出生后用丙酸睾酮（TP）处理的雌性大鼠）研究了性激素在这种学习中的作用。后一组、雄性对照组和阉割雄性大鼠均正确完成了任务。实验3的目的是确定在T型水迷宫中使用分类策略时两性之间可能存在的差异。总之，仅在发育过程中的空间学习中观察到了性别二态性。
