Moscato G
Scuola di Specializzazione in Allergologia e Immunologia Clinica, Università di Pavia.
G Ital Med Lav. 1989 Jan-Mar;11(1-2):33-5; discussion 37.
A relationship between stress and immunological system was first recognized in animals over 50 years ago. Several stressors, both physical and chemical, have been shown to be capable of affecting the activities of immunologically competent cells, particularly T-cell and natural killer cells (NK). The data presently available show that in humans also psychic stressors, as a bereavement or a divorce, may produce the same effects. There is evidence that such effects are mediated both by corticosteroid system and opioids neuropeptides via specific receptors found on T-cells.
50多年前，人们首次在动物身上认识到压力与免疫系统之间的关系。已表明，几种物理和化学应激源能够影响免疫活性细胞的活动，特别是T细胞和自然杀伤细胞（NK）。目前可得的数据表明，在人类中，诸如丧亲或离婚等精神应激源也可能产生同样的影响。有证据表明，此类影响是由皮质类固醇系统和阿片类神经肽通过T细胞上发现的特定受体介导的。
