Kang S K, Kim K S
Taehan Chikkwa Uisa Hyophoe Chi. 1989 Nov;27(11):1059-71.
Mucoceles are commonly occurring lesions of the oral mucous membrane and the most common lesion involving minor salivary tissue. The incidence of mucoceles is understandable since accessary salivary gland tissue is widely distributed throughout the oral mucous membrane and trauma to the mucosa, which causes their formation, occurs frequently. But only a few studies have been reported that describe its detailed features. This is a retrospective study on the salivary mucoceles in the oral mucous membrane and based on clinical chart, biopsy request and photomicroscopic finding of 112 patients treated by Dept. of Oral Surgery in Seoul National University Hospital, during the period of last 10 years. The results were as following. 1. The age range of the 112 patients was 2 to 60 years, with a peak incidence in the second decade and a gradual decline thereafter. Of the 112 patients, 49 (44%) were males and 63 (56%) were females, the male-to-female ratio being 1:1.29. 2. The majority of these lesions were located on the lower lip but occurred with lesser frequently on the buccal mucosa, floor of the mouth, tongue, retromolar region, upper lip. 3. Of the 112 patients, 107 (95%) were treated by excision and only 5 were treated by marsupialization. 18 of 112 cases had recurrence and the recurrence rate in this study was 16%. 4. Only 3 of the 112 cases revealed an epithelial lining. This incidence indicates that the mucus-extravasation by the damage of excretory duct rather than the ductal dilatation by mucus-retention may play a critical role in the production of these lesions. 5. In 81 cases (72.3%) minor salivary gland were included in the excision biopsy, specimen. Changes observed in the glandular tissue were atrophy and infiltration of chronic inflammatory cell, but the secretory function of gland was thought to be normal in most cases because the changes were mild.
黏液囊肿是口腔黏膜常见的病变,也是最常见的累及小涎腺组织的病变。黏液囊肿发病率较高是可以理解的,因为副涎腺组织广泛分布于整个口腔黏膜,且导致其形成的黏膜创伤频繁发生。但仅有少数研究报道过其详细特征。这是一项关于口腔黏膜涎腺黏液囊肿的回顾性研究,基于首尔国立大学医院口腔外科在过去10年中治疗的112例患者的临床病历、活检申请和显微镜检查结果。结果如下:1. 112例患者的年龄范围为2至60岁,发病高峰在第二个十年,此后逐渐下降。112例患者中,49例(44%)为男性,63例(56%)为女性,男女比例为1:1.29。2. 这些病变大多数位于下唇,但在颊黏膜、口底、舌、磨牙后区、上唇的发生率较低。3. 112例患者中,107例(95%)接受了切除治疗,仅5例接受了袋形缝合术。112例中有18例复发,本研究中的复发率为16%。4. 112例中仅有3例显示有上皮衬里。这一发生率表明,排泄管损伤导致的黏液外渗而非黏液潴留导致的导管扩张可能在这些病变的形成中起关键作用。5. 81例(72.3%)的切除活检标本中包含小涎腺。在腺组织中观察到的变化为萎缩和慢性炎性细胞浸润,但在大多数情况下,由于变化轻微,腺体的分泌功能被认为是正常的。