Bodner Lipa, Manor Esther, Joshua Ben-Zion, Shaco-Levy Ruthy
Department of Oral and Maxillofacial Surgery, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Institute of Human Genetics, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Pediatr Dermatol. 2015 Sep-Oct;32(5):647-50. doi: 10.1111/pde.12535. Epub 2015 Apr 6.
Mucoceles are common cystic lesions of the oral mucosa. Extravasation mucoceles (EMs) are mainly found in the lower lip of young patients, whereas retention mucoceles (RMs) are usually located in the cheek or palate of older patients. This study was undertaken to more fully characterize the clinicopathologic features of mucoceles in pediatric patients.
The records of 56 pediatric patients with mucoceles were included in the study. Age, sex, history of trauma, intraoral site, size, and method of treatment were evaluated. Histopathologically the lesions were classified as being EMs or RMs.
The age range was 1.5 to 16 years (mean age 11.2 yrs). Of the 56 patients, 24 (43%) were males and 32 (57%) were females, with a male:female ratio of 1:1.33. A history of trauma was recorded in 32 (57%) patients of the lower lip. The intraoral sites were the lower lip (38 [68%]), tongue (10 [18%]), and floor of the mouth (8 [14%]). Of the 56 patients, 44 (79%) were EM and 12 (21%) were ranulas. No RMs were found. Mucoceles ranged from 0.3 to 3.8 cm in diameter (mean 0.9 cm). The treatment of EMs was surgical excision. Cryosurgey, electrosurgery, and carbon dioxide laser were also used.
In contrast to adults, where EM and RM types can be found, among children all cases are of the EM type. The disparate site and age incidences of EMs and RMs of the oral mucosa suggest that these two types are not related and possibly have a different etiopathogenesis.
黏液囊肿是口腔黏膜常见的囊性病变。外渗性黏液囊肿（EMs）主要见于年轻患者的下唇，而潴留性黏液囊肿（RMs）通常位于老年患者的颊部或腭部。本研究旨在更全面地描述儿童黏液囊肿的临床病理特征。
本研究纳入了56例儿童黏液囊肿患者的记录。评估了年龄、性别、创伤史、口腔内部位、大小和治疗方法。组织病理学上，病变被分类为EMs或RMs。
年龄范围为1.5至16岁（平均年龄11.2岁）。56例患者中，24例（43%）为男性，32例（57%）为女性，男女比例为1:1.33。32例（57%）下唇患者有创伤史。口腔内部位为下唇（38例[68%]）、舌（10例[18%]）和口底（8例[14%]）。56例患者中，44例（79%）为EMs，12例（21%）为舌下囊肿。未发现RMs。黏液囊肿直径为0.3至3.8 cm（平均0.9 cm）。EMs的治疗方法为手术切除。也使用了冷冻手术、电外科手术和二氧化碳激光。
与可发现EM和RM类型的成人不同，儿童所有病例均为EM类型。口腔黏膜EMs和RMs不同的部位和年龄发病率表明，这两种类型无关，可能具有不同的发病机制。
