Division of Life Science and Applied Genomics Center, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, People's Republic of China.
Front Biosci (Landmark Ed). 2014 Jun 1;19(7):1117-50. doi: 10.2741/4271.
This study tracks the rise, evolution and post-evolution of the genetic information system through emergence of life. The major stages traversed include prebiotic synthesis, functional RNA selection by metabolite, RNA World, peptidated RNA world, co-evolution of genetic code and amino acid biosynthesis, last universal common ancestor, Darwinian evolution and synthetic life.
本研究通过生命的出现，追踪遗传信息系统的兴起、演变和后进化。所经历的主要阶段包括前生物合成、代谢物对功能性 RNA 的选择、RNA 世界、肽化 RNA 世界、遗传密码和氨基酸生物合成的共同进化、最后普遍共同祖先、达尔文进化和合成生命。
