生命的起源：从功能性 RNA 的选择到自然选择，以及更远。
Emergence of life: from functional RNA selection to natural selection and beyond.
机构信息
Division of Life Science and Applied Genomics Center, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, People's Republic of China.
出版信息
Front Biosci (Landmark Ed). 2014 Jun 1;19(7):1117-50. doi: 10.2741/4271.
DOI:10.2741/4271
PMID:24896340
Abstract
This study tracks the rise, evolution and post-evolution of the genetic information system through emergence of life. The major stages traversed include prebiotic synthesis, functional RNA selection by metabolite, RNA World, peptidated RNA world, co-evolution of genetic code and amino acid biosynthesis, last universal common ancestor, Darwinian evolution and synthetic life.
摘要
本研究通过生命的出现，追踪遗传信息系统的兴起、演变和后进化。所经历的主要阶段包括前生物合成、代谢物对功能性 RNA 的选择、RNA 世界、肽化 RNA 世界、遗传密码和氨基酸生物合成的共同进化、最后普遍共同祖先、达尔文进化和合成生命。
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