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肠结核:一例在结直肠活检时被误诊为克罗恩病的诊断难题病例。

Intestinal tuberculosis: a diagnostically-challenging case misdiagnosed as Crohn's disease at colorectal biopsy.

作者信息

Onorati M, Morganti D, Bocchi M, Colombo E, Petracco G, Uboldi P, Di Nuovo F

出版信息

Pathologica. 2014 Mar;106(1):22-5.

PMID:24897777
Abstract

The clinical presentation of two different digestive diseases such as Crohn's disease and intestinal tuberculosis may be so similar to induce a delay in correct diagnosis and appropriate treatment (immune suppression versus antibiotic therapy). Herein, we describe the case of a young man from Eastern Europe who came to our observation complaining of clinical symptoms initially misdiagnosed as an inflammatory bowel disease. It is important to keep in mind the possibility of an active tubercular disease, particularly in patients coming from countries endemic for the disease. Morphological findings of sarcoid-like granulomas at biopsy is not enough for a conclusive diagnosis of Crohn's disease, and tuberculosis should be ruled out on the basis of clinical information, laboratory tests and radiological imaging.

摘要

两种不同的消化系统疾病,如克罗恩病和肠结核,其临床表现可能非常相似,从而导致正确诊断和适当治疗的延迟(免疫抑制与抗生素治疗)。在此,我们描述了一名来自东欧的年轻男子的病例,他前来就诊,抱怨最初被误诊为炎症性肠病的临床症状。必须牢记存在活动性结核病的可能性,尤其是对于来自该病流行国家的患者。活检时发现类肉瘤样肉芽肿的形态学表现不足以确诊克罗恩病,应根据临床信息、实验室检查和放射影像学排除结核病。

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Pathologica. 2014 Mar;106(1):22-5.
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Misdiagnosis and Mistherapy of Crohn's Disease as Intestinal Tuberculosis: Case Report and Literature Review.克罗恩病误诊为肠结核的病例报告及文献复习
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