National Institute of Pharmaceutical Education and Research (NIPER), Department of Pharmacoinformatics , S.A.S. Nagar, Mohali, Punjab 160062 , India +91 0172 2214682-2211 ;
Expert Opin Ther Pat. 2014 Aug;24(8):893-912. doi: 10.1517/13543776.2014.926329. Epub 2014 Jun 5.
This review discusses the various drug therapeutic targets and latest technologies of anticancer patents from 10 Indian public-funded research organizations covering more than 150 esteemed institutes. We have identified and reported the leading assignee and inventors along with their collaboration network and, thereby, have analyzed the various patent trends, geographical distributions, citation maps, Derwent World Patents Index, international patent classification analysis and the like.
This article provides the insights of 1905 patent documents from 191 families and discusses in-depth anticancer technology through categorization studies at the level of drug discovery, drug development and treatment and diagnosis. In addition, various cancer targets were correlated with recent technologies so as to identify the white spaces for upcoming technologies.
Over a period of 13 years (1990 - 2013) the main focus of Indian cancer research was in the field of synthetic chemistry and natural extracts followed by the pharmaceutical compositions and combinations, whereas, the white spaces for future cancer remedy were identified from research in the areas of cancer stem cell lines, vaccines, gene therapy, nano formulations with targeted drug delivery systems as core and latest technologies.
本文讨论了来自 10 家印度公共资助研究机构的 150 多家知名机构的抗癌专利的各种药物治疗靶点和最新技术。我们已经确定并报告了主要的受让人以及发明人，以及他们的合作网络，从而分析了各种专利趋势、地理分布、引文图谱、德温特世界专利索引、国际专利分类分析等。
本文提供了 191 个家族的 1905 项专利文献的见解，并通过药物发现、药物开发和治疗以及诊断层面的分类研究深入讨论了抗癌技术。此外，还将各种癌症靶点与最新技术相关联，以确定未来技术的空白领域。
在 13 年的时间里（1990-2013 年），印度癌症研究的主要重点是在合成化学和天然提取物领域，其次是药物成分和组合，而未来癌症治疗的空白领域则来自癌症干细胞系、疫苗、基因治疗、纳米制剂与靶向药物输送系统等核心和最新技术领域的研究。
