Shankar Balasubramanyam, Narayanan Ramakrishna, Muralitharan Pushkaran, Ulaganathan Balamurugan
Department of Radiodiagnosis, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
BMJ Case Rep. 2014 Jun 4;2014:bcr2014204078. doi: 10.1136/bcr-2014-204078.
Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a clinicoradiological entity with varied aetiologies and having a typical course of evolution. We present a case of MERS evaluated with diffusion-weighted and diffusion tensor imaging along with various conventional sequences of MRI. At the time of presentation, the lesions in the splenium of corpus callosum and bilateral cerebral white matter showed diffusion restriction with reduced apparent diffusion coefficient and no reduction in fractional anisotropy (FA) values on diffusion tensor imaging; on follow-up diffusion restriction completely resolved with normalisation of the apparent diffusion coefficient. The normal to slightly increased FA values in the lesions may indicate that MERS is a non-degenerative disorder.
伴可逆性胼胝体压部病变的轻度脑炎/脑病（MERS）是一种病因多样、具有典型演变过程的临床放射学实体。我们报告一例MERS病例，该病例采用磁共振成像（MRI）的弥散加权成像、弥散张量成像及各种传统序列进行评估。在就诊时，胼胝体压部和双侧脑白质的病变在弥散加权成像上表现为弥散受限，表观扩散系数降低，弥散张量成像上的各向异性分数（FA）值无降低；随访时，弥散受限完全消失，表观扩散系数恢复正常。病变处FA值正常或略有升高可能表明MERS是一种非退行性疾病。
