用¹¹C-醋酸PET与¹⁸F-FDG PET成像评估舒尼替尼对1例转移性肾细胞癌患者的治疗效果比较
Assessment of Therapeutic Effect of Sunitinib by (11)C-Acetate PET Compared with FDG PET Imaging in a Patient with Metastatic Renal Cell Carcinoma.
作者信息
Oyama Nobuyuki, Takahara Noriko, Hasegawa Yoko, Tanase Kazuya, Miwa Yoshiji, Akino Hironobu, Okazawa Hidehiko, Kudo Takashi, Fujibayashi Yasuhisa, Yokoyama Osamu
机构信息
Department of Urology, University of Fukui, 23-3 Matsuoka-Shimoaizuki, Eiheiji, Fukui 910-1193 Japan.
Biomedical Imaging Research Center, University of Fukui, Eiheiji, Fukui Japan.
出版信息
Nucl Med Mol Imaging. 2011 Sep;45(3):217-9. doi: 10.1007/s13139-011-0084-x. Epub 2011 May 20.
Abstract
Although sunitinib shows a high response rate in patients with untreated metastatic renal cell carcinoma (mRCC), quite a few patients show no therapeutic effect. Therefore, it is crucial to distinguish the patients who respond to sunitinib from those who do not as early as possible after the administration of the therapy. We herein report a case of mRCC in which (11)C-acetate (AC) positron emission tomography (PET) showed an early therapeutic effect of sunitinib treatment 4 weeks after its administration.
摘要
虽然舒尼替尼在未经治疗的转移性肾细胞癌（mRCC）患者中显示出较高的缓解率，但仍有不少患者没有治疗效果。因此，在治疗开始后尽早区分对舒尼替尼有反应的患者和无反应的患者至关重要。我们在此报告一例mRCC病例，其中（11）C-醋酸盐（AC）正电子发射断层扫描（PET）显示舒尼替尼治疗4周后有早期治疗效果。
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