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铼-186放射性滑膜切除术在肘部弥漫性色素沉着绒毛结节性滑膜炎中的应用—— 1例多关节受累病例报告

Application of rhenium-186 radiosynovectomy in elbow diffuse pigmented villonodular synovitis. - a case report with multiple joint involvement.

作者信息

Koca Gokhan, Ozsoy Hakan, Atilgan Hasan Ikbal, Demirel Koray, Dincel Veysel Ercan, Korkmaz Meliha

机构信息

Department of Nuclear Medicine, Ankara Training and Research Hospital, Ankara, Turkey.

Department of Orthopedics and Traumatalogy, Ankara Training and Research Hospital, Ankara, Turkey.

出版信息

Nucl Med Mol Imaging. 2012 Sep;46(3):215-7. doi: 10.1007/s13139-012-0152-x. Epub 2012 Jul 13.

Abstract

After surgical therapy of diffuse pigmented villonodular synovitis (DPVNS), recurrence is seen in almost half of the patients. The effectiveness of radiosynovectomy (RSV) in preventing recurrence and complaints of DPVNS is well known. Elbow involvement in DPVNS is a very rare condition; therefore, RSV in elbow hasn't been experienced widely. The aim of this case report is to show the effectiveness of RSV with rhenium-186 (Re-186) sulfide colloid. We applied Re-186 sulfide colloid to the elbow joint of DPVNS patients six weeks after arthroscopic synovectomy. As a result, the patient did not have any complaints, and our findings are compatible with residue or recurrence on magnetic resonance imaging (MRI) in sixth and twentieth month controls after administration. We concluded that Re-186 is an effective adjuvant therapy for the prevention of recurrence and complaints.

摘要

弥漫性色素沉着绒毛结节性滑膜炎(DPVNS)手术治疗后,近半数患者会复发。放射性滑膜切除术(RSV)预防DPVNS复发及缓解症状的有效性已广为人知。肘关节受累于DPVNS是一种非常罕见的情况;因此,肘部的RSV尚未得到广泛应用。本病例报告的目的是展示硫化铼-186(Re-186)胶体进行RSV的有效性。我们在关节镜下滑膜切除术后六周,将Re-186硫化胶体应用于DPVNS患者的肘关节。结果,患者无任何不适,且在给药后第六个月和第二十个月的磁共振成像(MRI)检查中,我们的发现与残留或复发情况相符。我们得出结论,Re-186是预防复发和缓解症状的有效辅助治疗方法。

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本文引用的文献

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Diffuse pigmented villonodular synovitis: preliminary results with intralesional resection and p32 synoviorthesis.
Clin Orthop Relat Res. 2007 Jan;454:186-91. doi: 10.1097/01.blo.0000229345.57092.a2.

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