Moon Chan-Seok, Lee Chae Kwan, Hong Young Seoub, Ikeda Masayuki
Department of Industrial Health, College of Applied Sciences, Catholic University of Pusan, Bugok3-dong, Gumjeong-gu, Busan 609-757, Korea.
Asia Pac J Clin Nutr. 2014;23(2):219-24. doi: 10.6133/apjcn.2014.23.2.10.
This survey was initiated to examine possible coastal-inland differences in cadmium (Cd) burden in general Korean populations. In total, 268 healthy non-smoking middle-aged women (30 to 49 years; 88 residents in 8 coastal areas and 180 residents in 15 inland areas) participated in the study. They offered peripheral blood and spot urine samples so that cadmium in blood (Cd-B) and urine (Cd-U) were taken as exposure markers. Determination of Cd-B and Cd-U was carried out by graphite furnace atomic absorption spectrophotometry. With regard to Cd burden, geometric means for the coastal and inland residents were 1.70 and 1.72 μg/L for Cd-B, 1.54 and 1.00 μg/L for Cd-U as observed (Cd-U), 2.59 and 1.81 μg/g creatinine for Cd-U as corrected for creatinine (Cd-Ucr), respectively. Cd-U and Cd-Ucr were higher in the coastal areas than in inland areas. Reasons for higher Cd-U in the coastal areas than in the inland areas were are discussed in relation to major sources of Cd in daily life of the residents. Attention was paid to consumption of fish and shellfish in the coastal areas as major sources of dietary Cd intake. This study shows that Cd burdens were higher in coastal areas than in inland areas in Korea.
开展这项调查是为了研究韩国普通人群中镉(Cd)负荷在沿海和内陆地区可能存在的差异。共有268名健康的不吸烟中年女性(30至49岁;8个沿海地区的88名居民和15个内陆地区的180名居民)参与了该研究。她们提供了外周血和随机尿样,以便将血镉(Cd-B)和尿镉(Cd-U)作为暴露标志物。通过石墨炉原子吸收分光光度法测定Cd-B和Cd-U。关于镉负荷,沿海和内陆居民的血镉几何均值分别为1.70和1.72μg/L,观察到的尿镉(Cd-U)几何均值分别为1.54和1.00μg/L,校正肌酐后的尿镉(Cd-Ucr)几何均值分别为2.59和1.81μg/g肌酐。沿海地区的Cd-U和Cd-Ucr高于内陆地区。结合居民日常生活中镉的主要来源,讨论了沿海地区Cd-U高于内陆地区的原因。沿海地区食用鱼类和贝类作为膳食镉摄入的主要来源受到关注。这项研究表明,韩国沿海地区的镉负荷高于内陆地区。