Kong K L, Campbell C, Wagner K, Peterson A, Lanningham-Foster L
1 Department of Food Science and Human Nutrition, Iowa State University, Ames, USA.
2 Department of Statistics, Iowa State University, Iowa, USA.
J Dev Orig Health Dis. 2014 Jun;5(3):259-67. doi: 10.1017/S2040174414000117.
Few studies have investigated the impact of lifestyle interventions during pregnancy on post-partum weight retention and infant growth. Thirty seven previously non-exercising, overweight or obese pregnant women were randomly assigned to a walking intervention or non-intervention control. For the follow-up study, weight of the mother and weight, length and body composition of the infant were collected at 1 month post-partum (n=37) and 6 months post-partum (n=33). Analysis of variance and linear regression were conducted to determine the differences and association in maternal post-partum weight retention and child outcomes. At 6 months post-partum, weight retention of obese women in the intervention group (Int-OB) was -0.10±8.11 kg; while, obese women in the control group (Con-OB) was 6.35±7.47 kg. A significantly higher percentage of Con-OB women retained more than 5 kg at 6 months post-partum (P=0.046). Even though statistically non-significant between the groups, the growth trend observed among offspring of obese women in the control group was consistently higher than the offspring of obese women in the intervention group from birth to 6-months. Third trimester gestational weight gain rate significantly predicted 6-m weight-for-length z-score after controlling for birth weight, treatment group and pre-pregnancy body mass index (r 2=0.31, β=1.75, P=0.03). The reduced post-partum weight retention observed among the obese women in the intervention group may be explained in part by the lifestyle modification during pregnancy.
很少有研究调查孕期生活方式干预对产后体重滞留和婴儿生长的影响。37名先前不运动的超重或肥胖孕妇被随机分配到步行干预组或非干预对照组。在后续研究中，在产后1个月（n = 37）和产后6个月（n = 33）收集母亲的体重以及婴儿的体重、身长和身体成分。进行方差分析和线性回归以确定产妇产后体重滞留和儿童结局的差异及关联。在产后6个月时，干预组肥胖女性（Int - OB）的体重滞留为 -0.10±8.11千克；而对照组肥胖女性（Con - OB）为6.35±7.47千克。Con - OB组中在产后6个月体重滞留超过5千克的女性比例显著更高（P = 0.046）。尽管两组之间在统计学上无显著差异，但从出生到6个月，对照组肥胖女性后代的生长趋势始终高于干预组肥胖女性的后代。在控制出生体重、治疗组和孕前体重指数后，孕晚期体重增加率显著预测了6个月时的身长体重Z评分（r² = 0.31，β = 1.75，P = 0.03）。干预组肥胖女性产后体重滞留减少可能部分归因于孕期的生活方式改变。
