Bioengineering Undergraduate Program, University of California San Diego, La Jolla, CA, USA.
Department of Neurosciences, University of California San Diego, La Jolla, CA, USA ; Department of Physics, John Carroll University, University Heights OH, USA.
Front Neuroinform. 2014 May 20;8:56. doi: 10.3389/fninf.2014.00056. eCollection 2014.
We present a database client software-Neurovascular Network Explorer 1.0 (NNE 1.0)-that uses MATLAB(®) based Graphical User Interface (GUI) for interaction with a database of 2-photon single-vessel diameter measurements from our previous publication (Tian et al., 2010). These data are of particular interest for modeling the hemodynamic response. NNE 1.0 is downloaded by the user and then runs either as a MATLAB script or as a standalone program on a Windows platform. The GUI allows browsing the database according to parameters specified by the user, simple manipulation and visualization of the retrieved records (such as averaging and peak-normalization), and export of the results. Further, we provide NNE 1.0 source code. With this source code, the user can database their own experimental results, given the appropriate data structure and naming conventions, and thus share their data in a user-friendly format with other investigators. NNE 1.0 provides an example of seamless and low-cost solution for sharing of experimental data by a regular size neuroscience laboratory and may serve as a general template, facilitating dissemination of biological results and accelerating data-driven modeling approaches.
我们介绍了一个数据库客户端软件——神经血管网络浏览器 1.0（NNE 1.0），它使用基于 MATLAB（®）的图形用户界面（GUI）与我们之前发表的一篇文献中的 2 光子单血管直径测量数据库进行交互（Tian 等人，2010）。这些数据对于建模血液动力学反应特别有意义。NNE 1.0 由用户下载，然后在 Windows 平台上作为 MATLAB 脚本或独立程序运行。GUI 允许根据用户指定的参数浏览数据库，对检索到的记录进行简单的操作和可视化（例如平均值和峰归一化），并导出结果。此外，我们还提供了 NNE 1.0 的源代码。有了这个源代码，用户可以在给定适当的数据结构和命名约定的情况下将自己的实验结果录入数据库，从而以用户友好的格式与其他研究人员共享他们的数据。NNE 1.0 为常规大小的神经科学实验室提供了一种无缝且低成本的实验数据共享解决方案，并且可以作为一个通用模板，促进生物学结果的传播和加速数据驱动的建模方法。
