Yu Min-Chien, Lin Shun-Ku, Lai Jung-Nien, Wei James Cheng-Chung, Cheng Chieh-Yuan
School of Medicine, Chung Shan Medical University, Department of Integrated Chinese and Western Medicine, Chung Shan Medical University Hospital, Taichung City, Taiwan; Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei City 112, Taiwan.
Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei City 112, Taiwan; Department of Chinese Medicine, Taipei City Hospital, Ren-Ai Chinese Medicine Branch, Taipei, Taipei City 106, Taiwan.
J Ethnopharmacol. 2014 Aug 8;155(1):435-42. doi: 10.1016/j.jep.2014.05.049. Epub 2014 Jun 4.
Traditional Chinese medicines (TCM), when given for symptom relief, have gained widespread popularity among Sjögren׳s patients. The aim of this study was to analyze the utilization of TCM among Sjögren׳s patients in Taiwan.
The usage, frequency of service, and the Chinese herbal products prescribed among Sjögren׳s patients were evaluated in a cohort of 1,000,000 beneficiaries recruited from the National Health Insurance Research Database. The logistic regression method was employed to estimate the odds ratios (ORs) for utilization of a TCM.
More than 90% of Sjögren׳s patients received TCM out-patient services at least once during the study period. Patients with secondary Sjögren׳s syndrome were more likely to seek TCM treatment than those with primary Sjögren׳s syndrome. The aOR for those suffering from at least one rheumatologic disease was 1.56 (95% CI: 1.26-1.93), those with two rheumatologic diseases was 1.98 (95% CI: 1.29-3.04), while those with three or more rheumatologic diseases was 7.86 (95% CI: 1.09-56.58). Compared to Sjögren׳s patients who used no medical treatment, the aOR for those who took one type of conventional medication was 1.55 (95% CI: 1.25-1.92), those who took two types was 1.98 (95% CI: 1.60-2.47) while those who took three or more types was 2.91 (95% CI: 2.20-3.84). Qi-Ju-Di-Huang-Wan (Lycium Berry, Chrysanthemum, and Rehmannia Pill) was the most frequently prescribed formula among Sjögren׳s patients.
Qi-Ju-Di-Huang-Wan is the most commonly prescribed Chinese herbal formula for Sjögren׳s syndrome and its effects should be taken into account by healthcare providers.
用于缓解症状的传统中药在干燥综合征患者中广受欢迎。本研究旨在分析台湾干燥综合征患者对中药的使用情况。
从国民健康保险研究数据库招募的100万名受益人群中，评估干燥综合征患者的用药情况、服务频率以及所开具的中药产品。采用逻辑回归方法估计使用中药的比值比（OR）。
在研究期间，超过90%的干燥综合征患者至少接受过一次中药门诊服务。继发性干燥综合征患者比原发性干燥综合征患者更倾向于寻求中药治疗。患有至少一种风湿性疾病的患者的调整后比值比为1.56（95%置信区间：1.26 - 1.93），患有两种风湿性疾病的患者为1.98（95%置信区间：1.29 - 3.04），而患有三种或更多风湿性疾病的患者为7.86（95%置信区间：1.09 - 56.58）。与未接受任何药物治疗的干燥综合征患者相比，服用一种常规药物的患者的调整后比值比为1.55（95%置信区间：1.25 - 1.92），服用两种药物的患者为1.98（95%置信区间：1.60 - 2.47），而服用三种或更多药物的患者为2.91（95%置信区间：2.20 - 3.84）。杞菊地黄丸是干燥综合征患者中最常开具的方剂。
杞菊地黄丸是干燥综合征最常用的中药方剂，医疗服务提供者应考虑其疗效。
