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一名免疫功能正常幼儿的原发性肾曲霉菌病和黄色肉芽肿性肾盂肾炎

Primary renal aspergillosis and xanthogranulomatous pyelonephritis in an immuno-competent toddler.

作者信息

Shohab Durre, Hussain Ijaz, Khawaja Athar, Jamil Imran, Raja Nazar Ullah, Ahmed Faizan, Akhter Saeed

机构信息

Department of Urology and Kidney Transplant, Shifa International Hospital, Islamabad.

Department of Microbiology, Shifa International Hospital, Islamabad.

出版信息

J Coll Physicians Surg Pak. 2014 May;24 Suppl 2:S101-3.

Abstract

Aspergillosis is primarily a pulmonary disease so that renal aspergillosis is usually secondary to hematogenous spread from lungs. Primary renal aspergillosis, though a rare entity, is still seen in immuno-compromised individuals. Renal aspergillosis may lead to formation of focal abscesses, fungal bezoars and may cause ureteric obstruction. Treatment involves stabilization of patient and removal of fungal bezoars along with administration of anti-fungal agents. This report describes the case of localized primary renal aspergillosis with fungal bezoar formation in 2 years old immuno-competent child who presented in sepsis and acute renal failure and was successfully managed by nephroscopic removal of fungal bezoar and intravenous voriconazole. The other kidney required nephrectomy for xanthogranulomatous pyelonephritis.

摘要

曲霉病主要是一种肺部疾病,因此肾曲霉病通常继发于肺部的血行播散。原发性肾曲霉病虽然罕见,但仍可见于免疫功能低下的个体。肾曲霉病可能导致局灶性脓肿、真菌球形成,并可能引起输尿管梗阻。治疗包括稳定患者病情、清除真菌球以及使用抗真菌药物。本报告描述了一例2岁免疫功能正常儿童发生的局限性原发性肾曲霉病伴真菌球形成的病例,该患儿出现败血症和急性肾衰竭,通过肾镜清除真菌球和静脉注射伏立康唑成功治愈。另一例肾脏因黄色肉芽肿性肾盂肾炎而行肾切除术。

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