de Bekker Charissa, Merrow Martha, Hughes David P
*Department of Entomology and Biology, Center for Infectious Disease Dynamics, Pennsylvania State University, University Park, State College, PA 16802, USA; Institute of Medical Psychology, Faculty of Medicine, Ludwig Maximilians Universität München, 80336 Munich, Germany
*Department of Entomology and Biology, Center for Infectious Disease Dynamics, Pennsylvania State University, University Park, State College, PA 16802, USA; Institute of Medical Psychology, Faculty of Medicine, Ludwig Maximilians Universität München, 80336 Munich, Germany.
Integr Comp Biol. 2014 Jul;54(2):166-76. doi: 10.1093/icb/icu063. Epub 2014 Jun 6.
Co-evolution of parasites and their hosts has led to certain parasites adaptively manipulating the behavior of their hosts. Although the number of examples from different taxa for this phenomenon is growing, the mechanisms underlying parasite-induced manipulation of hosts' behavior are still poorly understood. The development of laboratory infections integrating various disciplines within the life sciences is an important step in that direction. Here, we advocate for such an integrative approach using the parasitic fungi of the genus Ophiocordyceps that induce an adaptive biting behavior in Camponotus ants as an example. We emphasize the use of behavioral assays under controlled laboratory conditions, the importance of temporal aspects of the behavior (possibly involving the circadian clock), and the need to approach colonizing parasites as organizations with a division of labor.
寄生虫与其宿主的共同进化导致某些寄生虫能适应性地操控宿主的行为。尽管来自不同生物类群的此类现象实例数量在不断增加，但寄生虫诱导宿主行为操控的潜在机制仍知之甚少。整合生命科学各学科的实验室感染研究发展是朝着这一方向迈出的重要一步。在此，我们以虫草属寄生真菌为例，倡导采用这种综合方法，该真菌能诱导弓背蚁产生适应性的咬噬行为。我们强调在可控实验室条件下进行行为测定，行为时间因素（可能涉及生物钟）的重要性，以及将寄生性寄生虫视为具有分工的组织来研究的必要性。
