钙通道阻滞剂、β受体阻滞剂和他汀类药物混合过量的处理
Management of a mixed overdose of calcium channel blockers, β-blockers and statins.
作者信息
Thakrar Reena, Shulman Rob, Bellingan Geoff, Singer Mervyn
机构信息
Department of Critical Care, University College London Hospital Foundation Trust, London, UK.
Pharmacy Department, University College London Hospital Foundation Trust, London, UK.
出版信息
BMJ Case Rep. 2014 Jun 6;2014:bcr2014204732. doi: 10.1136/bcr-2014-204732.
Abstract
We describe a case of extreme mixed overdose of calcium channel blockers, β-blockers and statins. The patient was successfully treated with aggressive resuscitation including cardiac pacing and multiorgan support, glucagon and high-dose insulin for toxicity related to calcium channel blockade and β-blockade, and ubiquinone for treating severe presumed statin-induced rhabdomyolysis and muscle weakness.
摘要
我们描述了一例钙通道阻滞剂、β受体阻滞剂和他汀类药物极度混合过量的病例。该患者通过积极的复苏治疗成功治愈，包括心脏起搏和多器官支持、使用胰高血糖素和高剂量胰岛素治疗与钙通道阻滞和β受体阻滞相关的毒性，以及使用辅酶Q10治疗严重的推测由他汀类药物引起的横纹肌溶解和肌肉无力。
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