Konstantinidis Ioannis, Kumar Tarun, Kher Udatta, Stanitsas Panagiotis D, Hinrichs James E, Kotsakis Georgios A
Department of Prosthodontics, TU Dresden, Dresden, Germany,
Clin Oral Investig. 2015 Mar;19(2):553-9. doi: 10.1007/s00784-014-1268-4. Epub 2014 Jun 8.
The purpose of this case series was to evaluate the new bone formation following guided bone regeneration (GBR) with a calcium phosphosilicate (CPS), alloplastic bone putty at peri-implant dehiscence defects and to assess survival rate of implants placed in the augmented sites after 12 months of function.
Implants were placed in patients exhibiting Seibert class I ridge defects resulting in peri-implant dehiscence defects. The defects were treated following GBR principles with the use of a CPS alloplastic bone graft putty in combination either with a collagen membrane or a titanium mesh. The height of each bony dehiscence was clinically measured at the time of implant placement and again during second-stage surgery. The percentage of complete defect coverage, frequency of adverse events, and risk factors for residual defect were determined.
Thirty-six implants were placed in 26 patients. Twenty-seven of the 36 sites employed a collagen membrane in conjunction with the CPS while the remaining nine sites utilized a titanium membrane. Mean gain in bone height was 3.23 ± 2.04 mm, with 75 % of the peri-implant defects achieving complete regeneration. A negative correlation was identified between patient age and complete coverage of the peri-implant defect (p = 0.026). The implant survival rate at 12 months was 97.22 %.
Use of CPS bone putty during delayed implant placement at peri-implant dehiscence sites either in combination with a collagen membrane or a titanium mesh results in predictable defect coverage.
The handling characteristics of CPS putty may simplify GBR protocol. Implants placed in conjunction with GBR have a very good survival rate after 1 year of follow-up.
本病例系列的目的是评估使用磷酸钙硅(CPS)这种异体骨替代物骨糊剂进行引导骨再生(GBR)后,种植体周围裂开性骨缺损处的新骨形成情况,并评估在功能行使12个月后,在增量部位植入的种植体的存活率。
将种植体植入表现为Seibert I类牙槽嵴缺损并导致种植体周围裂开性骨缺损的患者体内。按照GBR原则,使用CPS异体骨移植骨糊剂联合胶原膜或钛网对缺损进行处理。在种植体植入时及二期手术时,临床测量每个骨裂开的高度。确定完全缺损覆盖的百分比、不良事件的发生率以及残留缺损的危险因素。
26例患者共植入36枚种植体。36个部位中的27个使用胶原膜联合CPS,其余9个部位使用钛膜。骨高度的平均增加量为3.23±2.04mm,75%的种植体周围缺损实现了完全再生。患者年龄与种植体周围缺损的完全覆盖之间存在负相关(p = 0.026)。12个月时种植体的存活率为97.22%。
在种植体周围裂开部位延期植入种植体时,使用CPS骨糊剂联合胶原膜或钛网,可实现可预测的缺损覆盖。
CPS骨糊剂的操作特性可能会简化GBR方案。联合GBR植入的种植体在随访1年后具有非常好的存活率。