Hirachand Suspana, Bajracharya Junu, Pradhanang Sabi, Lama Sanju
Department of Pathology, KMCTH, Kathmandu, Nepal.
Department of Obstretics and Gynaecology, KMCTH, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2013 Jul-Sep;52(191):462-5.
Cancer of uterine cervix is a leading cause of mortality and morbidity among women worldwide. In developing countries it is the most common gynaecological cancer and one of the leading causes of cancer death among women. Pap smears are commonly used as cytological screening test for successful eradication of precancerous lesions, which has made it a routine procedure worldwide.
This descriptive study was conducted at Kathmandu Medical College Teaching Hospital, Kathmandu within a period of two years from January 2011 to December 2012. A total of 1369 cases were screened.
In this study, cytological examination of the smears showed 944 (68.95%) inflammatory smears, 301(21.99%) normal smears, 101(7.38%) atrophic smears, seven (0.51%) ASCUS, two (0.15%) LSIL, four (0.29%) HSIL and two (0.15%) squamous cell carcinoma. Radiation changes were seen in three (0.22%) cases. Of all the smears studied five (0.36%) cases were inadequate. Regarding ethnicity, incidence of epithelial cell abnormalities was high in Tamang (5 cases). Eleven cases (73.33%) of epithelial cell abnormalities were seen in patients from urban areas.
In country like Nepal with predominant rural population, screening and awareness programs with co-operation of media, non-government organizations and government should be formulated for early detection of cervical cancer.
子宫颈癌是全球女性死亡和发病的主要原因之一。在发展中国家，它是最常见的妇科癌症，也是女性癌症死亡的主要原因之一。巴氏涂片通常用作细胞学筛查测试，以成功根除癌前病变，这使其成为全球的常规程序。
这项描述性研究于2011年1月至2012年12月在加德满都的加德满都医学院教学医院进行，为期两年。共筛查了1369例病例。
在本研究中，涂片的细胞学检查显示944例（68.95%）为炎性涂片，301例（21.99%）为正常涂片，101例（7.38%）为萎缩性涂片，7例（0.51%）为非典型鳞状细胞不能明确意义（ASCUS），2例（0.15%）为低度鳞状上皮内病变（LSIL），4例（0.29%）为高度鳞状上皮内病变（HSIL），2例（0.15%）为鳞状细胞癌。3例（0.22%）出现放射性改变。在所有研究的涂片中，5例（0.36%）不合格。关于种族，塔芒族上皮细胞异常的发生率较高（5例）。11例（73.33%）上皮细胞异常出现在城市地区的患者中。
在像尼泊尔这样农村人口占主导的国家，应与媒体、非政府组织和政府合作制定筛查和提高认识计划，以便早期发现宫颈癌。
