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一种罕见的良性泪腺肿瘤恶性转化。

A rare malignant transformation of benign lacrimal tumor.

作者信息

Labh Rajan Kumar, Shrestha Gulshan Bahadur

机构信息

Biratnagar Eye Hospital, Biratnagar, Morang.

BP Koirala Lion's Center for Ophthalmic Studies, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2013 Jul-Sep;52(191):505-7.

PMID:24907960
Abstract

Lacrimal gland tumors are common in middle age group individuals. Proptosis is one of their common presentations. Sometimes the tumors may undergo malignant changes which if neglected can be life threatening. Here we present a case of 49 years male with gradual painless protrusion and diminution of vision in his right eye for eight years and more since last 2 months, with restriction of ocular motility in right lateral gaze. Expecting a benign mass, superolateral orbitotomy with excisional biopsy was done which astonishingly revealed carcinoma ex pleomorphic adenoma with components of adenocarcinoma and squamous cell carcinoma without any lymphovascular invasion. Proptosis and vision of the patient in right eye improved post excisional biopsy without any residual mass in respective follow ups.

摘要

泪腺肿瘤在中年人群中较为常见。眼球突出是其常见表现之一。有时肿瘤可能会发生恶变,若被忽视则可能危及生命。在此,我们报告一例49岁男性患者,右眼渐进性无痛性突出及视力减退8年余,近2个月来右侧凝视时眼球运动受限。考虑为良性肿块,遂行眶外上壁切开切除术及切除活检,结果令人惊讶地发现是多形性腺瘤恶变,伴有腺癌和鳞状细胞癌成分,无任何脉管侵犯。切除活检后患者右眼的眼球突出和视力得到改善,在随后的随访中未见任何残留肿块。

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