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患有化脓性汗腺炎患者的医疗保健利用模式和费用。

Health care utilization patterns and costs for patients with hidradenitis suppurativa.

机构信息

Department of Dermatology, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania.

Department of Public Health Sciences, Penn State Hershey, Hershey, Pennsylvania.

出版信息

JAMA Dermatol. 2014 Sep;150(9):937-44. doi: 10.1001/jamadermatol.2014.691.

Abstract

IMPORTANCE

Hidradenitis suppurativa (HS) is a chronic cutaneous disease with acutely painful flares that require appropriate and timely treatment.

OBJECTIVE

To assess how individuals with HS utilize medical care, especially emergency department (ED) care, a high-cost setting, and to describe the health care costs for this group.

DESIGN, SETTING, AND PARTICIPANTS: Cohort cost-identification study of 150 493 individuals with claims from the MarketScan medical claims database. Patients with claims for HS and psoriasis (16 736 and 110 266, respectively) and a control group with neither condition (23 491) during the study period, January 2008 to December 2010, were included.

EXPOSURES

An HS cohort was formed from all the patients who had 2 or more claims for HS (International Classification of Diseases, Ninth Revision [ICD-9] code 705.83) during the 3-year period. A psoriasis cohort was used as a comparison group, since it is another chronic inflammatory condition with prominent skin findings. This group included randomly selected patients who had 2 or more claims for psoriasis (ICD-9 code 696.1) during the 3-year period. A second control group included randomly selected patients who had no claims for either condition during the 3-year period. From these cohorts only patients that were continuously enrolled for the 3-year period were included.

MAIN OUTCOMES AND MEASURES

Health care utilization measures including inpatient length of stay, emergency department and outpatient visits, and number of days supplied of prescription medication were investigated. Cost variables were also investigated and included inpatient, outpatient, emergency department, prescription drug, and total all-cause health care expenditures, which were adjusted for inflation and reported in 2010 US dollars.

RESULTS

The largest component of the total 3-year cost for the HS group was inpatient cost (37.4%). In contrast, for the psoriasis group this was drug costs (46.5%) and for the control group, inpatient costs (40.9%). The proportion of people who were hospitalized in the HS cohort (15.8%) was higher than the psoriasis (10.8%) or control (8.6%) groups (P < .001). The proportion of patients who used the ED over the 3-year period was higher in the HS cohort (27.1%) than the psoriasis (17.4%) or control groups (17.2%) (P < .001). Similarly, the mean (SD) 3-year ED cost for the HS group was $2002 ($6632) and was higher than both comparison groups (P < .001). After adjustment for age, sex, and comorbidities, ED utilization remained higher in the HS group compared with the control (P < .001) and psoriasis (P = .02) cohorts.

CONCLUSIONS AND RELEVANCE

Hidradenitis suppurativa affects a younger, predominantly female population of patients. High-cost settings, such as ED and inpatient care, are used more frequently for patients with HS. Both patients and clinicians should be aware of this finding, and further research is needed to investigate the impact of health care utilization on patient outcomes.

摘要

重要性:化脓性汗腺炎(HS)是一种慢性皮肤病,伴有剧烈疼痛的急性发作,需要进行适当和及时的治疗。

目的:评估化脓性汗腺炎患者如何利用医疗保健,特别是急诊(ED)护理,这是一个高成本的环境,并描述该人群的医疗保健费用。

设计、地点和参与者:这是一项来自 MarketScan 医疗索赔数据库的 150493 名患者的队列成本识别研究。在研究期间(2008 年 1 月至 2010 年 12 月),包括有 HS 索赔(16736 例)和银屑病(110266 例)的患者队列,以及没有这两种疾病的对照组(23491 例)。

暴露:从 3 年内有 2 次或以上 HS 索赔(国际疾病分类,第 9 版[ICD-9]代码 705.83)的所有患者中形成了 HS 队列。银屑病队列被用作比较组,因为它是另一种具有明显皮肤表现的慢性炎症性疾病。该组包括在 3 年内有 2 次或以上银屑病索赔(ICD-9 代码 696.1)的随机选择的患者。第二个对照组包括在 3 年内没有任何一种疾病索赔的随机选择的患者。只有在 3 年内连续参保的患者才被纳入这些队列。

主要结果和措施:调查了医疗保健利用措施,包括住院时间、急诊和门诊就诊次数以及处方药供应天数。还调查了成本变量,包括住院、门诊、急诊、处方药和所有医疗保健总费用,并根据通胀进行了调整,并以 2010 年美元报告。

结果:HS 组的总成本中最大的组成部分是住院费用(37.4%)。相比之下,对于银屑病组,这是药物成本(46.5%),对于对照组,是住院费用(40.9%)。HS 队列中住院患者的比例(15.8%)高于银屑病(10.8%)或对照组(8.6%)(P<.001)。在 3 年期间,HS 队列中使用 ED 的患者比例(27.1%)高于银屑病(17.4%)或对照组(17.2%)(P<.001)。同样,HS 组的平均(SD)3 年 ED 费用为 2002 美元(6632 美元),高于两个对照组(P<.001)。在调整年龄、性别和合并症后,HS 组与对照组(P<.001)和银屑病组(P=.02)相比,ED 利用率仍较高。

结论和相关性:化脓性汗腺炎影响的是年轻、以女性为主的患者群体。ED 和住院治疗等高成本环境更频繁地被化脓性汗腺炎患者使用。患者和临床医生都应该意识到这一发现,需要进一步研究医疗保健利用对患者结局的影响。

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