Yu Yongmei, Guo Meiling, Han Xiangyu
Department of CT, First People's Hospital, Jining, 272000, Shandong, China.
Cell Biochem Biophys. 2014 Nov;70(2):1351-6. doi: 10.1007/s12013-014-0063-9.
The assessment of pancreatic cancer resectability is based mainly on the extent of the peripancreatic vasculature involvement with tumor mass. The 16-slice computed tomography (MSCT) and dual-source computed tomography (DSCT) were used in non-invasive imaging of the pancreas and the regional vessels in 48 pancreatic carcinoma patients. Both of these techniques were combined with contrast-enhanced angiography and post-scanning reconstruction of 2D and 3D images. Based on the degree of involvement revealed by these images, the pre-operative tumor resectability was determined. The CTA-based resectability was then correlated with the surgical and pathological findings for the evaluation of their sensitivity, specificity, negative and positive predictive values, and diagnostic accuracy. The study suggests that resectability based on dual-source CTA showed higher sensitivity, specificity, and diagnostic accuracy than that obtained from MSCTA scanning.
胰腺癌可切除性的评估主要基于肿瘤包块对胰腺周围脉管系统的累及程度。对48例胰腺癌患者采用16层螺旋CT（MSCT）和双源CT（DSCT）对胰腺及区域血管进行无创成像。这两种技术均结合了对比增强血管造影及扫描后二维和三维图像重建。根据这些图像显示的累及程度确定术前肿瘤的可切除性。然后将基于CTA的可切除性与手术及病理结果进行对比，以评估其敏感性、特异性、阴性和阳性预测值以及诊断准确性。研究表明，基于双源CTA的可切除性比MSCTA扫描具有更高的敏感性、特异性和诊断准确性。
