Psychiatric Clinic Ljubljana, 1260 Ljubljana Polje, Slovenia,
Psychiatr Danub. 2014 Jun;26(2):96-9.
Modern development trends in psychiatry incorporate greater care for patients and above all individualisation of therapeutic approaches. Therapeutic drug monitoring (TDM) for phenotyping and genotyping of drug metabolism are possible determinants of improved treatment efficacy, reduced adverse effects of psychotropic drugs, and enhanced treatment compliance. They render possible individual adjustment of psychopharmacological treatment and thus represent a small, but significant piece in the mosaic of creative psychopharmacotherapy.
现代精神病学的发展趋势更加关注患者,并且尤其注重治疗方法的个体化。药物代谢的表型和基因型的治疗药物监测(TDM)是提高治疗效果、减少精神药物不良反应和提高治疗依从性的可能决定因素。它们可以实现精神药理学治疗的个体化调整,因此是创造性精神药理学治疗马赛克中的一小部分,但却具有重要意义。