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正中开胸术后发生的羊种布鲁氏菌胸骨骨髓炎。

Brucella melitensis sternal osteomyelitis following median sternotomy.

作者信息

Chin Yoon T, Krishnan Monica, Burns Phillipa, Qamruddin Ahmed, Hasan Ragheb, Dodgson Andrew R

机构信息

Department of Microbiology, Manchester Royal Infirmary, Manchester M13 9WL, United Kingdom.

Cardiac Surgery Unit, Manchester Royal Infirmary, Manchester M13 9WL, United Kingdom.

出版信息

J Infect Chemother. 2014 Sep;20(9):574-6. doi: 10.1016/j.jiac.2014.04.011. Epub 2014 Jun 6.

Abstract

Human brucellosis, a zoonotic infection, may present with a range of symptoms but is rarely described as a cause of surgical site infections. We present the first reported case of Brucella melitensis causing sternal osteomyelitis of a midline sternotomy for a coronary artery bypass graft. The operation was performed in a non-endemic country but the patient had travelled to Syria immediately before surgery, where the infection was assumed to have been acquired. The infection resolved following treatment with doxycycline, rifampicin and gentamicin. We review the literature for surgical site infections related to Brucella species and discuss the infection control implications. Human brucellosis has the potential to cause surgical site infections and it should be in the differential diagnosis of any patient with a relevant exposure history presenting with a febrile illness and musculoskeletal findings.

摘要

人类布鲁氏菌病是一种人畜共患感染病,可能会出现一系列症状,但很少被描述为手术部位感染的病因。我们报告首例由羊种布鲁氏菌引起的冠状动脉搭桥术正中开胸术后胸骨骨髓炎病例。该手术在一个非布鲁氏菌病流行国家进行,但患者在手术前刚去过叙利亚,据推测其感染是在那里获得的。经强力霉素、利福平及庆大霉素治疗后感染得到控制。我们查阅了与布鲁氏菌属相关的手术部位感染的文献,并讨论了感染控制的意义。人类布鲁氏菌病有可能导致手术部位感染,对于任何有相关暴露史且出现发热性疾病和肌肉骨骼症状的患者,都应将其列入鉴别诊断范围。

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