Espinha Lívia P, Souza Fernando A, Capalbo Aretuza C, Bícego Kênia C, Macari Marcos, Gargaglioni Luciane H
Department of Animal Morphology and Physiology, São Paulo State University - (UNESP FCAV), Jaboticabal, SP, Brazil; National Institute of Science and Technology in Comparative Physiology (INCT-FisiologiaComparada), Brazil.
Department of Animal Morphology and Physiology, São Paulo State University - (UNESP FCAV), Jaboticabal, SP, Brazil.
Respir Physiol Neurobiol. 2014 Aug 15;200:50-6. doi: 10.1016/j.resp.2014.05.013. Epub 2014 Jun 5.
Pulmonary ventilation (V˙(E)), body temperature (Tb), mean arterial pressure (MAP), heart rate (f(H)) and metabolic rate (V˙(O2)) were measured in 10 (d10)- and 21 (d21)-day-old male and female chicks exposed to 7% CO2. Under normocapnia, V˙(E) was higher in d10 chicks than in d21 due to a higher tidal volume; in females a higher respiratory frequency (f(R)) was also observed. The d10 birds presented higher f(H) and V˙(O2). The d21 females showed the highest CO2 ventilatory response due to increased f(R). MAP did not change during hypercapnia while a hypercapnic bradycardia occurred, except in d21 females. Hypercapnia induced a drop in Tb in all groups and an increase in V˙(O2) in d21 males. Overall, no gender effect is observed in cardiorespiratory and metabolic variables in d10 and d21 chicks under normocapnia, the differences in V˙(E) and f(H) between ages may be related to distinct metabolic demands of these phases. The d21 female chicks seem to be more sensitive to hypercapnia.
在暴露于7%二氧化碳的10日龄（d10）和21日龄（d21）雄性和雌性雏鸡中测量了肺通气量（V˙(E)）、体温（Tb）、平均动脉压（MAP）、心率（f(H)）和代谢率（V˙(O2)）。在正常碳酸血症下，由于潮气量较高，d10雏鸡的V˙(E)高于d21雏鸡；在雌性中也观察到较高的呼吸频率（f(R)）。d10的雏鸡表现出较高的f(H)和V˙(O2)。d21的雌性由于f(R)增加而表现出最高的二氧化碳通气反应。除d21雌性外，高碳酸血症期间MAP没有变化，同时出现高碳酸血症性心动过缓。高碳酸血症导致所有组的Tb下降，d21雄性的V˙(O2)增加。总体而言，在正常碳酸血症下，d10和d21雏鸡的心肺和代谢变量未观察到性别效应，年龄之间V˙(E)和f(H)的差异可能与这些阶段不同的代谢需求有关。d21雌性雏鸡似乎对高碳酸血症更敏感。
