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非综合征患者的序列多生牙发育;1例罕见病例报告。

Sequential supernumerary teeth development in a non-syndromic patient; report of a rare case.

作者信息

Jafarian Mohammad, Nazemi Bahareh, Bargrizan Majid, Ramezani Jamileh, Ansari Ghassem

机构信息

Associated Professor, Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Assistant Professor, Department of Pediatric Dentistry, Faculty of Dentistry, Zanjan University of Medical Sciences, Zanjan, Iran.

出版信息

J Dent (Tehran). 2013 Nov;10(6):554-61. Epub 2013 Nov 30.

PMID:24910667
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4025438/
Abstract

Isolated impacted supernumerary teeth are quite rare, but they can be seen associated with several syndromes such as cleidocranial dysostosis or Gardner's syndrome. This article aims to discuss a case of sequential formation of supernumerary teeth with no other associated disease or syndrome. A 17-year-old Iranian male with 8 impacted supernumerary teeth was referred to the department of pediatric dental clinic at Shahid Beheshti Medical University in Tehran with a history of several impacted unerupted teeth. Repeated and periodical clinical and radiographic examinations revealed newly formed teeth buds in unusual dental ages. All extra teeth were associated with generalized enamel hypoplasia to some degree on their relative permanent adjacent teeth. The patient did not have any record of a systemic disease or any syndromic condition to relate his dental problem to. This rare condition involved repeated and continued formation of extra teeth out of the normal numbers and dental age evident in serial radiographs.

摘要

孤立的埋伏多生牙相当罕见,但可见于多种综合征,如锁骨颅骨发育不全或加德纳综合征。本文旨在讨论一例无其他相关疾病或综合征的多生牙序贯形成病例。一名17岁的伊朗男性,有8颗埋伏多生牙,因有几颗埋伏未萌出牙齿的病史,被转诊至德黑兰沙希德·贝赫什提医科大学儿童牙科诊所。反复的定期临床和影像学检查发现,在异常牙龄时有新形成的牙蕾。所有额外牙齿在相对应的恒牙邻牙上均有一定程度的广泛性釉质发育不全。该患者没有任何全身性疾病记录或任何综合征情况可将其牙齿问题与之关联。这种罕见情况表现为在连续X线片上明显出现超出正常数量和牙龄的额外牙齿反复持续形成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2048/4025438/fc1ca0088f03/jod-10-554f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2048/4025438/2eb4d881a1b2/jod-10-554f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2048/4025438/20bd702486f0/jod-10-554f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2048/4025438/879e7dd6a19c/jod-10-554f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2048/4025438/bebfad796621/jod-10-554f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2048/4025438/fc1ca0088f03/jod-10-554f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2048/4025438/2eb4d881a1b2/jod-10-554f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2048/4025438/20bd702486f0/jod-10-554f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2048/4025438/879e7dd6a19c/jod-10-554f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2048/4025438/bebfad796621/jod-10-554f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2048/4025438/fc1ca0088f03/jod-10-554f5.jpg

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本文引用的文献

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Bilaterally impacted mandibular supernumerary premolars associated with unusual clinical complications.双侧埋伏下颌额外前磨牙伴不寻常的临床并发症。
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Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood.
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Development. 2009 Jun;136(11):1939-49. doi: 10.1242/dev.033803.
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Multiple hyperodontia: report of a case with 17 supernumerary teeth with non syndromic association.多发性多生牙:17颗额外牙且无综合征关联病例报告
Med Oral Patol Oral Cir Bucal. 2009 May 1;14(5):E229-31.
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Multiple impacted teeth: report of 3 cases.多颗埋伏牙:3例报告
Eur J Dent. 2008 Jan;2(1):73-8.
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An adolescent patient with multiple impacted teeth.一名患有多颗阻生牙的青少年患者。
Angle Orthod. 2008 Nov;78(6):1110-8. doi: 10.2319/121007-581.1.
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Sequential supernumerary teeth in nonsyndromic patients: report of 3 cases.非综合征性患者的序列多生牙:3例报告
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Mesiodens with an unusual morphology and multiple impacted supernumerary teeth in a non-syndromic patient.一名非综合征患者的具有异常形态的正中多生牙和多颗埋伏额外牙。
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Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling.激活的上皮Wnt/β-连环蛋白信号传导可诱导小鼠牙齿持续生成。
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