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[替诺昔康酸与吲哚美辛治疗退行性关节疾病的双盲对照研究]

[Double-blind study of the effect of tiaprofenic acid in comparison with indomethacin in patients with degenerative joint diseases].

作者信息

Jajić I, Jajić Z

出版信息

Reumatizam. 1989;36(1-6):49-56.

PMID:2491404
Abstract

The research of the effect and tolerance of tiaprophenic acid comprised 32 patients (10 male and 22 female) aged 53.7 years on average. 16 patients were treated by tiaprophenic acid and the other 16 by indomethacin. Among them 23 patients suffered from gonarthrosis and 9 patients from coxarthrosis. The tested subjective and objective parameters were markedly improved in 66.7% and less well in further 10.4% of patients (a total of 77% examinees). Side-effects were more various and developed more frequently in patients treated by indomethacin.

摘要

关于噻丙吩酸疗效及耐受性的研究纳入了32例患者(男性10例,女性22例),平均年龄53.7岁。16例患者接受噻丙吩酸治疗,另外16例接受吲哚美辛治疗。其中23例患膝关节炎,9例患髋关节炎。在66.7%的患者中,所检测的主观和客观参数有显著改善,另有10.4%的患者改善程度稍差(总计77%的受试者)。吲哚美辛治疗的患者副作用更多且更频繁出现。

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