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澳大利亚维多利亚州部分复苏尝试对院外心脏骤停报告结果的影响:对Utstein式结果报告的启示

The impact of partial resuscitation attempts on the reported outcomes of out-of-hospital cardiac arrest in Victoria, Australia: implications for Utstein-style outcome reports.

作者信息

Nehme Z, Andrew E, Bernard S, Smith K

机构信息

Department of Research and Evaluation, Ambulance Victoria, Doncaster, Victoria, Australia; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Prahran, Victoria, Australia.

Department of Research and Evaluation, Ambulance Victoria, Doncaster, Victoria, Australia; Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Prahran, Victoria, Australia.

出版信息

Resuscitation. 2014 Sep;85(9):1185-91. doi: 10.1016/j.resuscitation.2014.05.032. Epub 2014 Jun 7.

Abstract

BACKGROUND

Success rates from cardiopulmonary resuscitation (CPR) are often quantified by Utstein-style outcome reports in populations who receive an attempted resuscitation. In some cases, evidence of futility is ascertained after a partial resuscitation attempt has been administered, and these cases reduce the overall effectiveness of CPR. We examine the impact of partial resuscitation attempts on the reported outcomes of out-of-hospital cardiac arrest (OHCA) in Victoria, Australia.

METHODS

Between 2002 and 2012, 34,849 adult OHCA cases of presumed cardiac aetiology were included from the Victorian Ambulance Cardiac Arrest Registry. Resuscitation attempts lasting ≤10min in cases which died on scene were defined as a partial resuscitation. We used logistic regression to identify factors associated with a partial resuscitation attempt in the emergency medical service (EMS) treated population. Survival outcomes with and without partial resuscitations were compared across included years.

RESULTS

The proportion of partial resuscitations in the overall EMS treated population increased significantly from 8.6% in 2002 to 18.8% in 2012 (p for trend<0.001), and were largely supported by documented evidence of irreversible death. Partial resuscitations were independently associated with older age, female gender, initial non-shockable rhythm, prolonged downtime, and lower skill level of EMS personnel. Selectively excluding partial resuscitations increased event survival by 7.6% (95% CI 4.1-11.2%), and survival to hospital discharge increased by 3.1% (95% CI 0.5-5.7%) in 2012 (p<0.001 for both).

CONCLUSION

In our EMS system, evidence of futility was often identified after the commencement of a partial resuscitation attempt. Excluding these events from OHCA outcome reports may better reflect the overall effectiveness of CPR.

摘要

背景

心肺复苏(CPR)成功率通常通过Utstein式结局报告来量化,这些报告针对的是接受复苏尝试的人群。在某些情况下,在进行了部分复苏尝试后确定了复苏无效的证据,这些情况降低了CPR的总体有效性。我们研究了部分复苏尝试对澳大利亚维多利亚州院外心脏骤停(OHCA)报告结局的影响。

方法

2002年至2012年期间,从维多利亚州救护车心脏骤停登记处纳入了34849例推测为心脏病因的成年OHCA病例。现场死亡病例中持续时间≤10分钟的复苏尝试被定义为部分复苏。我们使用逻辑回归来确定在接受紧急医疗服务(EMS)治疗的人群中与部分复苏尝试相关的因素。比较了纳入年份中进行和未进行部分复苏的生存结局。

结果

在接受EMS治疗的总体人群中,部分复苏的比例从2002年的8.6%显著增加到2012年的18.8%(趋势p<0.001),并且在很大程度上有不可逆死亡的书面证据支持。部分复苏与年龄较大、女性、初始不可电击心律、停机时间延长以及EMS人员技能水平较低独立相关。选择性排除部分复苏使2012年的事件生存率提高了7.6%(95%CI 4.1 - 11.2%),出院生存率提高了3.1%(95%CI 0.5 - 5.7%)(两者p<0.001)。

结论

在我们的EMS系统中,往往在部分复苏尝试开始后才确定复苏无效的证据。从OHCA结局报告中排除这些事件可能更好地反映CPR的总体有效性。

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