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澳大利亚墨尔本的青年人群院外心脏骤停。

Out-of-hospital cardiac arrests in young adults in Melbourne, Australia.

机构信息

Ambulance Victoria, Australia.

出版信息

Resuscitation. 2011 Jul;82(7):830-4. doi: 10.1016/j.resuscitation.2011.03.008. Epub 2011 Mar 23.

Abstract

BACKGROUND

Characteristics and outcomes of out-of-hospital cardiac arrest (OHCA) in young adults are not well described in Australia.

METHODS

A 10-year retrospective case review of all OHCA in young adults (aged 16-39) and not witnessed by EMS, was performed using data from the Victorian Ambulance Cardiac Arrest Registry (VACAR).

RESULTS

Between 2000 and 2009 there were 30,006 adult cardiac arrests of which 3912 (13%) were in this age group. The median (IQR) age was 30 (25-35) years for both sexes with a 3:1 male to female ratio. Overdose was the most common precipitant (33.5%) followed by presumed cardiac (20%). Bystander CPR occurred in 21.2%, EMS median response time was 7 min and resuscitation was attempted in 36% of OHCAs. The presenting rhythm was asystole in 84.6%, PEA in 8.8% and VF/VT in 6.6%. Survival to hospital discharge, for all cause OHCA where resuscitation was attempted, was similar for young adult and older adults (8.8% vs 8.4%, p=0.2). However, for presumed cardiac aetiology OHCA, young adults had a greater proportion of survivors (14.8% vs 9.0%, p<0.001). Cardiac arrest with shockable rhythm (VF/pulseless VT) had a survival rate of 31.2% for young adults compared to 18.5% for older adults (p<0.001).

CONCLUSION

Survival to hospital discharge rates from OHCA due to a 'presumed cardiac' precipitant in young adults is much better than older adults, however, all cause OHCA survival is similar. Multi agency novel upstream preventive strategies aimed at tackling drug overdose may reduce this aetiology of OHCA and save lives.

摘要

背景

在澳大利亚,青年人院外心脏骤停(OHCA)的特征和结局尚未得到很好描述。

方法

采用维多利亚救护车心脏骤停登记处(VACAR)的数据,对所有非由EMS 目击的青年人(年龄 16-39 岁)OHCA 进行了 10 年回顾性病例分析。

结果

2000 年至 2009 年间,共有 30006 例成人心脏骤停,其中 13%(3912 例)发生在该年龄组。男女两性的中位(IQR)年龄均为 30(25-35)岁,男女比例为 3:1。最常见的诱发因素是药物过量(33.5%),其次是推定的心脏性(20%)。旁观者实施 CPR 的占 21.2%,EMS 中位反应时间为 7 分钟,36%的 OHCA 尝试了复苏。初始节律为无脉性电活动(PEA)的占 8.8%,VF/VT 的占 6.6%。所有尝试复苏的 OHCA 患者,无论病因如何,存活至出院的比例在青年组和老年组相似(8.8%对 8.4%,p=0.2)。然而,对于推定的心脏性病因 OHCA,青年组的幸存者比例更高(14.8%对 9.0%,p<0.001)。伴有可除颤节律(VF/无脉性 VT)的心脏骤停患者,青年组的存活率为 31.2%,而老年组为 18.5%(p<0.001)。

结论

由于“推定的心脏”原因导致青年人 OHCA 存活至出院的比例明显优于老年人,但所有病因 OHCA 的存活率相似。多机构新颖的上游预防策略旨在解决药物过量问题,可能会减少 OHCA 的这种病因,并挽救生命。

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