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赢创-美因茨-眼保健研究(EMECS):筛查调查的设计与实施

The Evonik-Mainz-Eye-Care-Study (EMECS): design and execution of the screening investigation.

作者信息

Barleon Lorenz, Wahl Jochen, Morfeld Peter, Deters Claudia, Lichtmeβ Andrea, Haas-Brähler Sibylle, Müller Uta, Breitstadt Rolf, Pfeiffer Norbert

机构信息

Department of Ophthalmology, University Medical Center, Johannes-Gutenberg-University, Mainz, Germany.

Institute for Occupational Medicine, Environmental Medicine and Prevention Research, University of Cologne, Köln, Germany; Institute for Occupational Epidemiology and Risk Assessment of Evonik Industries, Essen, Germany.

出版信息

PLoS One. 2014 Jun 10;9(6):e98538. doi: 10.1371/journal.pone.0098538. eCollection 2014.

Abstract

PURPOSE

To determine if screening for major ophthalmological diseases is feasible within the frame of routine occupational medicine examinations in a large working population.

METHODS

13037 employees of Evonik Industries aged 40 to 65 years were invited to be screened for major ophthalmological diseases (glaucoma, age related macular degeneration and diabetic retinopathy between June 2007 and March 2008 within an extended setting of occupational medicine. Ophthalmological examinations consisted of visual acuity, objective refraction, pachymetry, tonometry, perimetry (frequency doubling technology), confocal scanning laser ophthalmoscopy and digital fundus photography. Participants responded to a questionnaire addressing history of ocular and general diseases and social history.

RESULTS

4183 participants (961 female and 3222 male) were examined at 13 different sites. Response rates for eligible persons at those sites ranged from 17.9 to 60.5% but were in part limited by availability of examination slots. Average age of participants was 48.4 ± 5.4 years (mean ± SD). 4147 out of 4183 subjects (99.1%) had a visual acuity ≥ 0.5 in the better eye and 3665 out of 4183 (87.6%) subjects had a visual acuity ≥ 0.8 in the better eye. 1629 participants (38.9%) had previously not been seen by an ophthalmologist at all or not within the last three years.

CONCLUSION

This article describes the study design and basic characteristics of study participants within a large occupational medicine based screening study for ophthalmological diseases. Response rates exceeded expectations and were limiting examination capacity. Meaningful data could be obtained for almost all participants. We reached participants who previously had not received ophthalmic care. Thus, ophthalmological screening appears to be feasible within the frame of routine occupational medicine examinations.

摘要

目的

确定在大规模劳动人口的常规职业医学检查框架内筛查主要眼科疾病是否可行。

方法

邀请赢创工业公司的13037名40至65岁员工在2007年6月至2008年3月期间的职业医学扩展检查中接受主要眼科疾病(青光眼、年龄相关性黄斑变性和糖尿病视网膜病变)的筛查。眼科检查包括视力、客观验光、角膜测厚、眼压测量、视野检查(频率加倍技术)、共焦扫描激光眼底镜检查和数字眼底摄影。参与者回答了一份关于眼部和全身疾病史以及社会史的问卷。

结果

在13个不同地点对4183名参与者(961名女性和3222名男性)进行了检查。这些地点符合条件者的应答率在17.9%至60.5%之间,但部分受到检查时段可用性的限制。参与者的平均年龄为48.4±5.4岁(均值±标准差)。4183名受试者中有4147名(99.1%)较好眼的视力≥0.5,4183名受试者中有3665名(87.6%)较好眼的视力≥0.8。1629名参与者(38.9%)此前从未看过眼科医生,或者在过去三年内未看过。

结论

本文描述了一项基于职业医学的大型眼科疾病筛查研究的研究设计和研究参与者的基本特征。应答率超出预期,但限制了检查能力。几乎所有参与者都能获得有意义的数据。我们接触到了此前未接受过眼科护理的参与者。因此,眼科筛查在常规职业医学检查框架内似乎是可行的。

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