Odes H S, Fraser D
Department of Medicine, Ben-Gurion University of Negev, Beer Sheva, Israel.
Public Health Rev. 1989;17(4):297-319.
We have reviewed the epidemiology of ulcerative colitis in Israel. Ulcerative colitis is twice as common as Crohn's disease, and has increased in frequency in both sexes and in all ethnic sections of the Jewish population since 1960. The disease is more prevalent in European- and American-born Jews than in Asian- and African-born Jews and Israeli-born Jews, but this difference appears to be decreasing in magnitude. With the exception of European- and American-born Jews, ulcerative colitis is less prevalent in Israel than in Jews living elsewhere. Major regional differences in disease severity by sex, and in the extent of colonic involvement, were detected. Colorectal cancer occurs less frequently in colitis patients in Israel than elsewhere. The peak age at onset is 15-30 years, with Israeli-born colitis patients having a significantly earlier mean age at onset. Genetic and environmental causative factors are incompletely understood. The disease has become more prevalent in the Arab population.
我们回顾了以色列溃疡性结肠炎的流行病学情况。溃疡性结肠炎的发病率是克罗恩病的两倍，自1960年以来，在犹太人口的所有性别和所有种族群体中发病率均有所上升。在欧洲和美国出生的犹太人中，该疾病比在亚洲和非洲出生的犹太人以及以色列出生的犹太人中更为普遍，但这种差异的幅度似乎正在减小。除了欧洲和美国出生的犹太人外，溃疡性结肠炎在以色列的发病率低于生活在其他地方的犹太人。在疾病严重程度方面，按性别以及结肠受累范围检测到主要的地区差异。以色列结肠炎患者患结直肠癌的频率低于其他地方。发病的高峰年龄为15至30岁，以色列出生的结肠炎患者发病的平均年龄明显更早。对遗传和环境致病因素的了解尚不全面。该疾病在阿拉伯人群中也变得更加普遍。
