López-Rocha Eunice, Rodríguez-Mireles Karen, Gaspar-López Arturo, Del Rivero-Hernández Leonel, Segura-Méndez Nora
Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Av. Cuauhtémoc 330 06720 México, DF.
Rev Alerg Mex. 2014 Apr-Jun;61(2):59-64.
Sensitization to mites and cockroach are a common cause of respiratory allergy, especially in children. There is little information about its cross-reactivity with shrimp, which is common in adult patients.
To determine the frequency of sensitization to house dust mites (Dermatophagoides pteronyssinus, Dermatophagoides farinae) and cockroach species Periplaneta americana, in adult patients attending to a third level hospital and to determine the frequency of sensitization to shrimp in patients with positive skin test to house dust mite and/or cockroach, in patients with clinical manifestations suggestive of allergy to shrimp.
A retrospective study was done in which results were reviewed of 672 patients clinical records, attending to the Allergy and Clinical Immunology department in a third level hospital, those patients with positive skin test results to Dermatophagoides and/or Periplaneta americana were investigated for sensitization to shrimp through Prick-to-Prick test.
Data from 672 patients were obtained, 69.8% (469) males, with a mean age of 33.5 years. Dermatophagoides positivity was 72.2% (486/672), and its relationship with other invertebrates that also have tropomyosin was 5.6% (4.9% with cockroach and 0.74% with shrimp).
In our population, house dust mite sensitization was similar to that reported in the international literature. There was low positivity to cockroach, probably due to geographical conditions. There is very little information about shrimp's cross-reactivity with Dermatophagoides, despite its clinical significance, which requires more specific studies such as measurement of specific IgE to tropomyosin.
对螨虫和蟑螂过敏是呼吸道过敏的常见原因，尤其是在儿童中。关于其与虾的交叉反应的信息很少，而虾过敏在成年患者中很常见。
确定在一家三级医院就诊的成年患者中对屋尘螨（粉尘螨、屋尘螨）和美洲大蠊的致敏频率，并确定对屋尘螨和/或蟑螂皮肤试验呈阳性、有虾过敏临床表现的患者中对虾的致敏频率。
进行了一项回顾性研究，回顾了672例患者的临床记录，这些患者在一家三级医院的过敏与临床免疫科就诊，对那些对粉尘螨和/或美洲大蠊皮肤试验呈阳性的患者，通过点刺试验调查其对虾的致敏情况。
获得了672例患者的数据，男性占69.8%（469例），平均年龄33.5岁。粉尘螨阳性率为72.2%（486/672），其与其他也含有原肌球蛋白的无脊椎动物的关联率为5.6%（与蟑螂的关联率为4.9%，与虾的关联率为0.74%）。
在我们的研究人群中，屋尘螨致敏情况与国际文献报道相似。蟑螂阳性率较低，可能是由于地理条件所致。尽管虾与粉尘螨的交叉反应具有临床意义，但关于这方面的信息非常少，这需要更具体的研究，如测量针对原肌球蛋白的特异性IgE。
