Katyukhin L N
I. M. Sechenov Institute of Evolutional Physiology and Biochemistry, the Russian Academy of Sciences, St. Petersburg, Russia,
Bull Exp Biol Med. 2014 May;157(1):116-8. doi: 10.1007/s10517-014-2505-1. Epub 2014 Jun 11.
We developed a method for evaluation of membrane permeability for water based on the analysis of osmotic permeability profiles of red blood cells. Deformability of completely spherulated erythrocytes changed in a dose-dependent manner during formation of artificial water pores (by nystatin) and blocking (by HgCl2) of the existing ones.
我们基于对红细胞渗透渗透率曲线的分析,开发了一种评估水膜通透性的方法。在人工水孔形成(由制霉菌素)和现有水孔阻断(由氯化汞)过程中,完全球形化红细胞的变形能力呈剂量依赖性变化。