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中国大陆精神分裂症的流行情况:来自流行病学调查的证据。

The prevalence of schizophrenia in mainland China: evidence from epidemiological surveys.

机构信息

School of Public Health of Guangxi Medical University, Nanning, Guangxi, China.

出版信息

Acta Psychiatr Scand. 2014 Oct;130(4):244-56. doi: 10.1111/acps.12296. Epub 2014 Jun 11.

DOI:10.1111/acps.12296
PMID:24916190
Abstract

OBJECTIVE

Schizophrenia is a severe mental disorder. Its prevalence appears inconsistent in different regions of China; thus, we conducted this meta-analysis to estimate the prevalence of schizophrenia in mainland China.

METHOD

Studies on the prevalence of schizophrenia in mainland China were identified from electronic databases up to July 2013. Meta-analysis was used for prevalence of schizophrenia estimate.

RESULTS

For lifetime prevalence of schizophrenia, prevalence of 5.44 per 1000 (overall), 5.33 per 1000 (males), 5.51 per 1000 (females), 6.60 per 1000 (urban) and 4.73 per 1000 (rural) were estimated; there was no significant difference between males and females, while prevalence for urban dwellers was higher than for rural (OR=1.44, 95%CI: 1.30-1.59). For point prevalence of schizophrenia, prevalence of 4.62 per 1000 (overall), 4.63 per 1000 (males), 4.95 per 1000 (females), 5.15 per 1000 (urban) and 4.44 per 1000 (rural) were estimated; no statistical difference was found in males and females, but prevalence for urban dwellers was higher than for rural (OR=1.20; 95%CI: 1.02-1.41).

CONCLUSION

The prevalence estimate results were consistent with the international prevalence estimate of schizophrenia in mainland China. There was no significant difference between males and females, while prevalence for urban dwellers was higher than for rural.

摘要

目的

精神分裂症是一种严重的精神障碍。其在中国不同地区的流行率似乎不一致;因此,我们进行了这项荟萃分析,以估计中国大陆精神分裂症的流行率。

方法

从电子数据库中检索截至 2013 年 7 月中国大陆精神分裂症患病率的研究。采用荟萃分析估计精神分裂症的患病率。

结果

终生精神分裂症患病率为 5.44/1000(总体)、5.33/1000(男性)、5.51/1000(女性)、6.60/1000(城市)和 4.73/1000(农村);男性和女性之间无显著差异,而城市居民的患病率高于农村居民(OR=1.44,95%CI:1.30-1.59)。时点患病率为 4.62/1000(总体)、4.63/1000(男性)、4.95/1000(女性)、5.15/1000(城市)和 4.44/1000(农村);男性和女性之间无统计学差异,但城市居民的患病率高于农村居民(OR=1.20;95%CI:1.02-1.41)。

结论

本患病率估计结果与中国大陆精神分裂症的国际患病率估计一致。男性和女性之间无显著差异,而城市居民的患病率高于农村居民。

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