低碳水化合物饮食评分不能预测儿童和青少年的代谢综合征：德黑兰脂质与葡萄糖研究。

Low carbohydrate diet score does not predict metabolic syndrome in children and adolescents: Tehran Lipid and Glucose Study.

作者信息

Eslamian Ghazaleh, Mirmiran Parvin, Asghari Golaleh, Hosseini-Esfahani Firoozeh, Yuzbashian Emad, Azizi Fereidoun

机构信息

Students Research Committee, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2)Nutrition and Endocrine Research Center, Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.3)Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Arch Iran Med. 2014 Jun;17(6):417-22.

PMID:24916527

Abstract

BACKGROUND

The aim of the study was to evaluate the ability of a low carbohydrate diet score (LCD) to predict the occurrence of the metabolic syndrome (MetS) and its components in a group of Tehrani children and adolescents after 3.6 years of follow-up.

METHODS

Diet scores were calculated using a validated semi-quantitative food frequency questionnaire for participants aged 6-19 years, selected from the Tehran Lipid and Glucose Study cohort. The LCD was calculated based on intake of carbohydrate, monounsaturated fatty acids, refined grains and vegetable protein intake, expressed as a percentage of energy as well as fiber, n3/n6 polyunsaturated fatty acids and glycemic load. The higher the score, the more closely the participant's diet followed the pattern of LCD. The incidence of MetS and its components was calculated three years later.

RESULTS

The mean age of the participants was 13.8 ± 3.6 years and 45.4% were boys. The incidence rates of MetS, high blood pressure, high triglycerides, low HDL-C, abdominal obesity, and high blood glucose were 7.5%, 11%, 15%, 6.9%, 18.3%, and 12.3%, respectively. Compared to those in the lowest quartile of LCD score, after adjusting for age, sex, physical activity, and energy intake, participants in the highest quartile of LCD score had odds ratios of 0.74 (95% CI: 0.24-2.28), 1.16 (95% CI: 0.47-2.81), 0.55(95% CI: 0.21-1.44), 0.49 (95% CI: 0.11-2.08), 0.91 (95% CI: 0.42-1.98), and 1.28 (95% CI: 0.51-3.20) with the incidence of MetS, high blood pressure, high triglycerides, low HDL-C, abdominal obesity, and high blood glucose.

CONCLUSION

No association was found between LCD and the incidence of MetS or its components in children and adolescents in Tehran after 3.6 years of follow up.

摘要

背景

本研究旨在评估低碳水化合物饮食评分（LCD）预测一组德黑兰儿童和青少年在3.6年随访后代谢综合征（MetS）及其组分发生情况的能力。

方法

使用经过验证的半定量食物频率问卷，对从德黑兰血脂与血糖研究队列中选取的6至19岁参与者计算饮食评分。LCD根据碳水化合物、单不饱和脂肪酸、精制谷物和植物蛋白的摄入量计算得出，以能量百分比以及纤维、n3/n6多不饱和脂肪酸和血糖负荷表示。分数越高，参与者的饮食越符合LCD模式。三年后计算MetS及其组分的发病率。

结果

参与者的平均年龄为13.8±3.6岁，45.4%为男孩。MetS、高血压、高甘油三酯、低高密度脂蛋白胆固醇（HDL-C）、腹型肥胖和高血糖的发病率分别为7.5%、11%、15%、6.9%、18.3%和12.3%。与LCD评分最低四分位数的参与者相比，在调整年龄、性别、身体活动和能量摄入后，LCD评分最高四分位数的参与者发生MetS、高血压、高甘油三酯、低HDL-C、腹型肥胖和高血糖的比值比分别为0.74（95%置信区间：0.24 - 2.28）、1.1（95%置信区间：0.47 - 2.81）、0.55（95%置信区间：0.21 - 1.44）、0.49（95%置信区间：0.11 - 2.08）、0.91（95%置信区间：0.42 - 1.98）和1.28（95%置信区间：0.51 - 3.20）。