Stolkarts I Z, Zlotnik E I, Khmara N F, Kupriianenko R A, Krasil'nikova N Ia
Vopr Neirokhir. 1978 Jan-Feb(1):13-9.
In studying the content of lactic and pyruvic acids in the cerebrospinal fluid of 31 patients during operation for intracranial aneurysms under halothane anesthesia, the authors established that the performance of these operations under protection of deep (40 mm Hg) and prolonged (up to 2 hrs 25 min) artificial arterial hypotension in an uncomplicated course of the surgical intervention was not attended with hypoxic damage of the brain. The danger of hypoxia developing became greater when acute disturbances of blood flow in the cerebral arteries (clipping of a vessel, spasm) occurred in the period of hypotension.
在研究31例颅内动脉瘤手术患者在氟烷麻醉下脑脊液中乳酸和丙酮酸的含量时,作者发现,在手术干预过程顺利的情况下,在深度(40毫米汞柱)和长时间(长达2小时25分钟)人工动脉低血压的保护下进行这些手术,并未伴随脑缺氧损伤。当在低血压期间发生脑动脉血流急性紊乱(血管夹闭、痉挛)时,缺氧发展的危险会增加。