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2007年至2010年期间死亡的韩国儿科癌症患者临终关怀的激进趋势。

Trends in the aggressiveness of end-of-life care for Korean pediatric cancer patients who died in 2007-2010.

作者信息

Park June Dong, Kang Hyoung Jin, Kim Young Ae, Jo MinKyoung, Lee Eun Sook, Shin Hee Young, Yun Young Ho

机构信息

Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.

Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea; Cancer Institute, Seoul National University College of Medicine, Seoul, Korea.

出版信息

PLoS One. 2014 Jun 12;9(6):e99888. doi: 10.1371/journal.pone.0099888. eCollection 2014.

Abstract

BACKGROUND

In light of the Korean Supreme Court's 2009 ruling favoring a patient's right to die with dignity, we evaluated trends in aggressive care in a cohort of pediatric cancer patients. Methods We conducted a population-based retrospective study that used administrative data for patients who died in 2007-2010 among the 5,203 pediatric cancer patients registered at the Korean Cancer Central Registry (KCCR) during 2007-2009.

RESULTS

In the time period covered, 696 patients died. The proportion who had received chemotherapy in the last 30 days of life decreased from 58.1% to 28.9% (P<0.001), those who received new chemotherapy in the same time period decreased from 55.2% to 15.1% (P<0.001), and those who received treatment in the last 2 weeks of life decreased from 51.4% to 21.7% (P<0.001). In the last 30 days of life, the proportion of patients whose hospital admission period was over 14 days increased from 70.5% to 82.5% (P = 0.03), the proportion who received cardiopulmonary resuscitation decreased from 28.6% to 9.6% (P<0.001), and we found no statistically significant trends in the proportion of emergency department visits, intensive care unit admissions, or mechanical ventilation.

CONCLUSIONS

In this study, in contrast with earlier ones, the aggressiveness of end-of-life care of Korean pediatric cancer patients decreased dramatically.

摘要

背景

鉴于韩国最高法院2009年做出的支持患者尊严死权利的裁决,我们评估了一组儿童癌症患者积极治疗的趋势。方法我们进行了一项基于人群的回顾性研究,使用了2007 - 2009年在韩国癌症中心登记处(KCCR)登记的5203例儿童癌症患者中2007 - 2010年死亡患者的管理数据。

结果

在涵盖的时间段内,696例患者死亡。在生命的最后30天接受化疗的比例从58.1%降至28.9%(P<0.001),在同一时期接受新化疗的比例从55.2%降至15.1%(P<0.001),在生命的最后2周接受治疗的比例从51.4%降至21.7%(P<0.001)。在生命的最后30天,住院时间超过14天的患者比例从70.5%增至82.5%(P = 0.03),接受心肺复苏的比例从28.6%降至9.6%(P<0.001),并且我们发现急诊就诊、重症监护病房入院或机械通气比例无统计学显著趋势。

结论

在本研究中,与早期研究不同,韩国儿童癌症患者临终关怀的积极程度大幅下降。

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