Akoria Obehi Aituaje, Arhuidese Isibor James
Department of Medicine, University of Benin and University of Benin Teaching Hospital, Benin City, Nigeria.
Ann Afr Med. 2014 Jul-Sep;13(3):104-13. doi: 10.4103/1596-3519.134383.
The Roll Back Malaria (RBM) Partnership converged in Abuja in 2000. In 2005, Nigeria adopted artemisinin-based combination therapies (ACTs) as first-line therapy for uncomplicated malaria. It was determined that by 2010, 80% of persons with malaria would be effectively treated.
To describe household practices for malaria treatment in Benin City; to explore demographic characteristics that may influence use of ACTs.
Multistage sampling technique was used to select households from each of the three local government areas in Benin City. Adult respondents were interviewed. Household reference persons (HRPs) were defined by International Labour Organization categories. Data were collected between December 2009 and February 2010 and were analyzed using Statistical Package for the Social Sciences Version 16.0, at a significance level of P < 0.05 (2-tailed).
Of the 240 households selected, 217 were accessible, and respondents from 90% of these recalled the most recent episode (s) of malaria. One-third of malaria episodes had occurred in children younger than 5 years. ACTs were used in 4.9% of households; sulfadoxine-pyrimethamine was the chief non-ACT antimalarial, followed by artemisinin monotherapies. Patent medicine stores were the most common sources of antimalarial medicines (38.2%), followed by private hospitals (20.3%) and private pharmacies (10.6%). Only 8.3% of households got their medicines from government hospitals. Having a HRP in managerial or professional categories was associated with a 6 times higher odds of using ACTs, compared to other occupational categories [odds ratio (OR) 5.8; confidence interval (CI) 1.470-20.758, P = 0.016]. Fathers' tertiary or higher education was significantly associated with ACT use, but not mothers' (OR 0.054, CI 0.006-0.510; P = 0.011 and OR 0.905, CI 0.195-4.198; P = 0.898, respectively).
Ten years after the historic Abuja meeting, only 5% of households in Benin City used ACTs for the treatment of malaria, sourcing medicines chiefly from patent medicine stores and private hospitals. Fathers' level of education was significantly associated with ACT use. Interventions to eliminate malaria from Nigeria should mainstream the men folk and health care providers outside government hospitals, in line with the Nigerian reality.
减疟伙伴关系（RBM）于2000年在阿布贾成立。2005年，尼日利亚采用以青蒿素为基础的联合疗法（ACTs）作为单纯性疟疾的一线治疗方法。目标是到2010年，80%的疟疾患者能得到有效治疗。
描述贝宁城家庭治疗疟疾的做法；探讨可能影响ACTs使用的人口统计学特征。
采用多阶段抽样技术从贝宁城三个地方政府辖区中各选取家庭。对成年受访者进行访谈。家庭参考人员（HRPs）根据国际劳工组织的类别进行界定。在2009年12月至2010年2月期间收集数据，并使用社会科学统计软件包第16.0版进行分析，显著性水平为P < 0.05（双侧）。
在选取的240个家庭中，217个家庭可接触到，其中90%的受访者回忆起了最近的疟疾发作情况。三分之一的疟疾发作发生在5岁以下儿童中。4.9%的家庭使用ACTs；周效磺胺 - 乙胺嘧啶是主要的非ACT抗疟药，其次是青蒿素单一疗法。成药商店是抗疟药最常见的来源（38.2%），其次是私立医院（20.3%）和私人药店（10.6%）。只有8.3%的家庭从政府医院获取药品。与其他职业类别相比，担任管理或专业类别的家庭参考人员使用ACTs的几率高6倍[比值比（OR）5.8；置信区间（CI）1.470 - 20.758，P = 0.016]。父亲的高等教育与ACTs的使用显著相关，但母亲的则不然（OR分别为0.054，CI 0.006 - 0.510；P = 0.011和OR 0.905，CI 0.195 - 4.198；P = 0.898）。
在具有历史意义的阿布贾会议召开十年后，贝宁城只有5%的家庭使用ACTs治疗疟疾，药品主要从成药商店和私立医院获取。父亲的教育水平与ACTs的使用显著相关。根据尼日利亚的实际情况，尼日利亚消除疟疾的干预措施应将男性和政府医院以外的医疗服务提供者纳入主流。
