Pihlblad Matthew S, Demer Joseph L
Department of Ophthalmology, SteinEye Institute, UCLA, Los Angeles, California.
Department of Ophthalmology, SteinEye Institute, UCLA, Los Angeles, California; Department of Neurology, UCLA, Los Angeles; Neuroscience Interdepartmental Program, UCLA, Los Angeles; Bioengineering Interdepartmental Program, UCLA, Los Angeles.
J AAPOS. 2014 Jun;18(3):235-40. doi: 10.1016/j.jaapos.2014.01.017.
To evaluate the incidence and features of hypertropia in abducens nerve palsy.
The records of consecutive patients with unilateral, isolated, previously unoperated abducens nerve palsy were reviewed for binocular alignment on cover testing, Krimsky measurement, or Hess screen testing. Patients with associated cranial nerve palsy (including bilateral abducens palsies), orbital disease, myasthenia gravis, Horner syndrome, hemiplegia, cerebellar signs, arteritis, or previous strabismus surgery were excluded. Control subjects underwent complete examination to confirm normality.
A total of 79 patients were included (40 males; mean age 49.2 years). Hypertropia in lateral or central gazes was present in 15 of 79 cases (19%) on alternate cover or Krimsky testing, in 32 of 56 cases (57%) on Hess screen testing, and absent in all 30 normal controls. Of cases with hypertropia, the mean of the greatest hypertropia in lateral or central gaze on was 5.0(Δ) ± 2.3(Δ) (standard deviation; range, 1(Δ)-8(Δ)) routine clinical examination, and 5.8(Δ) ± 4.2(Δ) (range, 2(Δ)-24(Δ)) on Hess screen testing. Of 39 cases with partial abducens palsy evaluated by Hess screen testing, the ipsilesional eye was hypertropic in 24 (61%) and hypotropic in 15 cases (39%).
Small-angle hypertropia is common in isolated, unilateral abducens and does not imply existence of multiple cranial neuropathies or skew deviation.
评估外展神经麻痹中上斜视的发生率及特征。
回顾性分析连续性单眼、孤立性、既往未手术的外展神经麻痹患者的病历,通过遮盖试验、克里姆斯基测量法或赫斯屏试验评估双眼视轴对齐情况。排除伴有其他颅神经麻痹(包括双侧外展神经麻痹)、眼眶疾病、重症肌无力、霍纳综合征、偏瘫、小脑体征、动脉炎或既往斜视手术史的患者。对照组进行全面检查以确认正常。
共纳入79例患者(40例男性;平均年龄49.2岁)。交替遮盖试验或克里姆斯基测量法显示,79例中有15例(19%)在向外侧或中央注视时有上斜视;赫斯屏试验显示,56例中有32例(57%)存在上斜视,30例正常对照者均无。存在上斜视的病例中,常规临床检查时向外侧或中央注视时最大上斜视度数的平均值为5.0(三棱镜度)±2.3(三棱镜度)(标准差;范围,1(三棱镜度)-8(三棱镜度)),赫斯屏试验时为5.8(三棱镜度)±4.2(三棱镜度)(范围,2(三棱镜度)-24(三棱镜度))。在通过赫斯屏试验评估的39例部分性外展神经麻痹病例中,患侧眼上斜者24例(61%),下斜者15例(39%)。
小角度上斜视在孤立性、单侧外展神经麻痹中很常见,并不意味着存在多发性颅神经病变或斜视偏斜。