Epstein J, Ganz P R, Seitz R, Jutzi M, Schaerer C, Michaud G, Agbanyo F, Smith G, Prosser I, Heiden M, Saint-Marie I, Oualikene-Gonin W, Hamaguchi I, Yasuda N
Office of Blood Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA.
Vox Sang. 2014 Nov;107(4):416-9. doi: 10.1111/vox.12166. Epub 2014 Jun 13.
National Regulatory Authorities (NRAs) establish deferral criteria for donors with risk factors for transfusion transmissible infections (TTI). In most jurisdictions, epidemiological data show that men who have sex with men (MSM) have a significantly higher rate of TTI than the general population. Nevertheless, changes from an indefinite donor deferral for MSM have been considered in many countries in response to concerns over a perceived discrimination and questioning of the scientific need. Changes to MSM donor deferral criteria should be based on sound scientific evidence. Safety of transfusion recipients should be the first priority, and stakeholder input should be sought.
国家监管机构（NRAs）为具有输血传播感染（TTI）风险因素的献血者制定延期标准。在大多数司法管辖区，流行病学数据显示，男男性行为者（MSM）的TTI发生率明显高于普通人群。然而，鉴于对感知到的歧视以及对科学必要性的质疑的担忧，许多国家已考虑改变对MSM无限期延期献血的政策。对MSM献血延期标准的改变应基于可靠的科学证据。输血受者的安全应是首要优先事项，并且应征求利益相关者的意见。
