Check J H, Chase J S, Wu C H, Adelson H G
Department of Obstetrics and Gynecology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA.
Am J Obstet Gynecol. 1989 Feb;160(2):405-6. doi: 10.1016/0002-9378(89)90458-4.
A case is described of a woman with ovarian failure and documented atrophic ovaries in whom ovulation was achieved with the use of high-dose estrogen and human menopausal gonadotropins. The proposed mechanism involves a reduction in the elevated gonadotropins, which restored an adequate number of receptors. Thus sensitivity to exogenous menotropins was reestablished.
本文描述了一例患有卵巢功能衰竭且经证实卵巢萎缩的女性病例，该患者通过使用高剂量雌激素和人绝经期促性腺激素实现了排卵。推测的机制包括降低升高的促性腺激素水平，这使受体数量恢复到足够水平。因此，对外源性促性腺激素的敏感性得以重建。
