Yarborough Mark
Bioethics Program, University of California-Davis, Sacramento, California, USA
FASEB J. 2014 Sep;28(9):3841-6. doi: 10.1096/fj.13-246603. Epub 2014 Jun 13.
To enjoy the public's trust, the research community must first be clear about what it is expected to do and then avoid the incidents that prevent it from meeting those expectations. Among other things, there are expectations that published scientific results will be reliable, that research has the potential to contribute to the common good, and that research will be conducted ethically. Consequently, the scientific community needs to avoid lapses that prevent it from meeting these three expectations. This requires a strong commitment to trustworthy research practices, as well as mechanisms that diminish lapses that inevitably occur in complex endeavors such as scientific research. The author presents a model to assess the strength of commitment to trustworthy research and explores proven quality assurance mechanisms that can diminish lapses in research injurious to the public's trust. Some mechanisms identify in advance ways that things can go wrong so that steps can be taken to prevent them from going wrong in the first place. Other mechanisms investigate past errors or near misses to discover their causes so that they can be addressed to avoid similar future instances. The author explains why such methods are useful to efforts to promote research worthy of the public's trust.
为赢得公众的信任,科研界首先必须清楚自己应该做什么,然后避免那些阻碍其达到这些期望的事件。除其他事项外,人们期望发表的科学成果是可靠的,研究有潜力为公共利益做出贡献,并且研究将以符合道德的方式进行。因此,科学界需要避免出现那些妨碍其实现这三项期望的失误。这需要对值得信赖的研究实践做出坚定承诺,以及建立一些机制来减少在诸如科学研究这样的复杂活动中不可避免会出现的失误。作者提出了一个模型来评估对值得信赖的研究的承诺力度,并探索了一些经过验证的质量保证机制,这些机制可以减少有损公众信任的研究失误。一些机制提前识别事情可能出错的方式,以便能够采取措施首先防止它们出错。其他机制则调查过去的错误或险些发生的失误,以发现其原因,从而能够加以解决,避免未来出现类似情况。作者解释了为什么这些方法对促进值得公众信任的研究的努力是有用的。